Skip to main content
. 2019 Feb 28;16(3):234–240. doi: 10.1016/j.jor.2019.02.022

Table 2.

Main characteristics of studies included in this meta-analysis.

First Author
 Country (Ethnicity)
 Genotyping
Method
 SOC
 Case/Control
 Cases
 Controls
 MAFs
 HWE
Genotypes
 Allele
 Genotypes
 Allele
rs2234693 TT CT CC T C TT CT CC T C
Bergink 200312 Netherlands(Caucasian) PCR-RFLP PB 1483/687 434 737 312 1605 1361 225 333 129 783 591 0.430 0.767
Xue 200413 China(Asian) PCR-RFLP PB 55/176 17 23 15 57 53 57 87 32 201 151 0.429 0.905
Jin 200414 Korea(Asian) PCR-RFLP PB 151/397 61 68 22 190 112 152 183 62 487 307 0.386 0.575
Yan 200415 China(Asian) PCR-RFLP NA 53/176 10 24 21 44 66 54 82 40 190 162 0.460 0.408
Yang 200916 China(Asian) PCR-RFLP PB 41/40 14 17 10 45 37 12 23 5 47 33 0.412 0.238
Tian 200917 China(Asian) PCR-RFLP PB 38/40 16 15 7 47 29 15 16 9 46 34 0.425 0.250
Rianch 201018 UK (Caucasian) TaqMan PB 445/862 77 245 123 399 491 167 442 253 776 948 0.549 0.292
Spain(Caucasian) 272/802 53 140 79 246 298 179 394 229 752 852 0.531 0.699
Spain(Caucasian) 254/473 46 143 65 235 273 80 217 176 377 569 0.601 0.349
Borgonio-Cuadra 201219 Mexico(Mixed) PCR-RFLP PB 115/117 52 49 14 153 77 51 50 16 152 82 0.350 0.507
Liu 201420 China(Asian) PCR-RFLP PB 98/196 30 41 27 101 95 63 97 36 223 169 0.431 0.900
Dai 201421 China(Asian) TaqMan PB 469/514 167 217 85 551 387 198 242 74 638 390 0.379 0.996
Feng 201722 China(Asian) PCR-RFLP PB 520/1042 260 209 51 729 311 665 327 50 1657 427 0.204 0.234
Present 2018
 Iran(Asian)
 PCR-RFLP
 PB
 90/90
 30
 42
 18
 102
 78
 24
 37
 29
 85
 95
 0.527
 0.096
rs9340799
AA
 GA
 GG
 A
 G
 AA
 GA
 GG
 A
 G
Bergink 200312 Netherlands(Caucasian) PCR-RFLP PB 1483/687 643 682 158 1968 998 372 263 52 1007 367 0.267 0.560
Xue 200413 China(Asian) PCR-RFLP PB 55/176 21 24 10 66 44 40 82 54 162 190 0.539 0.408
Jin 200414 Korea(Asian) PCR-RFLP PB 151/397 98 49 4 245 57 256 126 15 638 156 0.196 0.917
Yan 200415 China(Asian) PCR-RFLP NA 55/176 15 23 17 53 57 32 87 57 151 201 0.571 0.905
Yang 200916 China(Asian) PCR-RFLP PB 41/40 28 11 2 67 15 24 13 3 61 19 0.237 0.516
Tian 200917 China(Asian) PCR-RFLP PB 38/40 18 16 4 52 24 6 21 13 33 47 0.587 0.598
Borgonio-Cuadra 201219 Mexico(Mixed) PCR-RFLP PB 115/117 70 41 4 181 49 62 47 8 171 63 0.269 0.821
Liu 201420 China(Asian) PCR-RFLP PB 98/196 36 43 19 115 81 49 92 55 190 202 0.515 0.398
Dai 201421 China(Asian) TaqMan PB 469/514 288 152 29 728 210 348 155 19 851 193 0.184 0.736
Feng 201722 China(Asian) PCR-RFLP PB 520/1042 276 201 43 796 818 618 366 58 1660 1388 0.666 ≤0.001
Present 2018 Iran(Asian) PCR-RFLP PB 90/90 51 28 11 130 50 45 32 13 122 58 0.322 0.077

PCR–RFLP: polymerase chain reaction restriction fragment length polymorphism; PB: population based; NA: not applicable; SOC: source of controls; MAFs: minor allele frequencies; HWE: Hardy-Weinberg Equilibrium.