An official website of the United States government
Here's how you know
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Canonical pathway for α2β1 signaling. Upon collagen or laminin binding to integrin α2β1, a series of signaling events occur to promote survival, proliferation, migration, and invasion. Integrins are often recycled to provide a refreshed pool of integrins to the surface membrane.