Fig. 1.

Uncorrected (A) and corrected (B) surface maps of differences in the AIs for cortical thickness between patients with MDD and NCs. As determined by a GLM analysis, differences in AIs are presented on left inflated cortical surfaces. Dark gray indicates gyri; light gray indicates sulci. The color bar represents t values ranging from 1.5 to 3. Red to yellow indicates increased AIs in the MDD group compared with those in the NC group; a closer proximity to yellow indicates a greater difference. The numerals refer to the cluster numbers listed in Table 2. The anatomical locations of the peak vertex of clusters 1 and 2 are the caudal middle frontal cortex (CMFC) and superior frontal cortex (SFC), respectively. Otherwise, the lateral surface of cluster 2 involves a portion of rostral middle frontal cortex (RMFC). (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)