Figure 5.

Expression PVT1, miR-424-5p, CARM1, MMP-2, MMP-9, Bcl-2, and Bax in NSCLC (n = 80) and Adjacent Tissues

(A) miR-424-5p expression and mRNA expression of PVT1, CARM1, MMP-2, MMP-9, Bcl-2, and Bax in tissues. (B) Western blot analysis for protein expression. (C) Protein expression of PVT1, CARM1, MMP-2, MMP-9, Bax, and Bcl-2 in tissues. *p < 0.05, compared with the adjacent tissues. Data are means ± SD from three independent experiments and analyzed by paired t test. PVT1, plasmacytoma variant translocation 1; miR-424-5p, mircoRNA-424-5p; CARM1, co-activator-associated arginine methyltransferase 1; MMP-2, matrix metallopeptidase-2; MMP-9, matrix metallopeptidase; Bcl-2, B cell lymphoma 2; Bax, Bcl2-associated X protein; NSCLC, non-small cell lung cancer.