Table 1.
Demographic data of the participants.
| ALS patients (N = 60) | Normal controls (N = 60) | P value | |
|---|---|---|---|
| Mean Age in Years (range) | 48.77(26–69) | 48.15(24–70) | 0.73 |
| Male/female | 39/21 | 39/21 | 1.00 |
| Education Level in Years (range) | 12.2 (5–18) | 12.7 (6–19) | 0.48 |
| MoCA Score (range) | 27.38 (26–30) | 27.63 (26–30) | 0.29 |
| Limb/bulbar/both onset | 47/12/1 | – | – |
| Classic/LMN-D/UMN-D/PLS/PMA | 43/7/7/2/1 | – | – |
| Mean Disease Duration in Months (range) | 21.05(2−132) | – | – |
| Mean ALSFRS-R (range) | 32.62(16–45) | – | – |
| Mean Disease Progression Rate (range) | 1.36(0.02–6.50) | – | – |
MoCA = Montreal Cognitive Assessment; The ALS patients were subdivided into 5 phenotypes: classic, lower motor neuron dominant (LMN-D), upper motor neuron dominant (UMN-D), primary lateral sclerosis (PLS) and progressive muscular atrophy (PMA).