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. 2018 Dec 29;276(3):827–836. doi: 10.1007/s00405-018-05263-x

Table 2.

Characteristics of OPSCC patients according to p16 status by HPV infection and daily lifestyle habits

All cases (n = 100) p16 positive (n = 34) p16 negative (n = 66) p value
High-risk-type HPV DNA status < 0.001
 Positive 46 34 (100) 14 (21.2)
 Negative 54 0 (0) 52 (78.8)
HPV types
 HPV 16 38 25 13
 HPV 33 4 3 1
 HPV 35 2 2
 HPV 56 1 1
 HPV 58 2 2
 HPV 67 1 1
 Low-risk-type HPV 6 1 1
Smoking consumption 0.001
 Less than 40 pack-years 53 26 (76.5) 27 (40.1)
 Equal to or more than 40 pack-years 47 8 (23.5) 39 (59.9)
Alcohol consumption (g/day) 0.003
 0–39.9 43 22 (64.7) 21 (31.8)
 ≥ 40 57 12 (35.5) 45 (68.2)

HPV human papilloma virus