Table 2.
Characteristics of OPSCC patients according to p16 status by HPV infection and daily lifestyle habits
All cases (n = 100) | p16 positive (n = 34) | p16 negative (n = 66) | p value | |
---|---|---|---|---|
High-risk-type HPV DNA status | < 0.001 | |||
Positive | 46 | 34 (100) | 14 (21.2) | |
Negative | 54 | 0 (0) | 52 (78.8) | |
HPV types | ||||
HPV 16 | 38 | 25 | 13 | |
HPV 33 | 4 | 3 | 1 | |
HPV 35 | 2 | 2 | ||
HPV 56 | 1 | 1 | ||
HPV 58 | 2 | 2 | ||
HPV 67 | 1 | 1 | ||
Low-risk-type HPV 6 | 1 | 1 | ||
Smoking consumption | 0.001 | |||
Less than 40 pack-years | 53 | 26 (76.5) | 27 (40.1) | |
Equal to or more than 40 pack-years | 47 | 8 (23.5) | 39 (59.9) | |
Alcohol consumption (g/day) | 0.003 | |||
0–39.9 | 43 | 22 (64.7) | 21 (31.8) | |
≥ 40 | 57 | 12 (35.5) | 45 (68.2) |
HPV human papilloma virus