Table 1.
Vitamin D target genes.
| Gene | Primary? | Type(s) of assays | Citation |
|---|---|---|---|
| CAMP | Yes | qPCR | Liu et al., 2007 |
| CYP24A1 | – | qPCR | Liu et al., 2007 |
| CYP24A1 | – | qPCR | Wu et al., 2007 |
| CYP27B1 | – | qPCR | Wu et al., 2007 |
| CD14 | Yes | qPCR | Moeenrezakhanlou et al., 2008 |
| ITGAM | Yes | qPCR | Moeenrezakhanlou et al., 2008 |
| ALOX5 | No | qPCR | Matsunawa et al., 2009 |
| CAMP | Yes | qPCR | Matsunawa et al., 2009 |
| CD14 | Yes | qPCR | Matsunawa et al., 2009 |
| CYP24A1 | – | qPCR | Matsunawa et al., 2009 |
| FANCE | Yes | ChIP-seq & FAIRE-seq display, qPCR | Seuter et al., 2013b |
| HBEGF | Yes | ChIP-seq & FAIRE-seq display, qPCR | Seuter et al., 2013b |
| NFKBIA | Yes | ChIP-seq & FAIRE-seq display, qPCR | Seuter et al., 2013b |
| PDCD1LG2 | Yes | ChIP-seq & FAIRE-seq display, qPCR | Seuter et al., 2013b |
| TMEM37 | Yes | ChIP-seq & FAIRE-seq display, qPCR | Seuter et al., 2013b |
| BHLHE40 | – | ChIP-seq & FAIRE-seq display, qPCR | Seuter et al., 2013c |
| CAMP | Yes | ChIP-seq & FAIRE-seq display, qPCR | Seuter et al., 2013a |
| CD93 | Yes | ChIP-seq & FAIRE-seq display, qPCR | Seuter et al., 2013a |
| DUSP10 | Yes | ChIP-seq & FAIRE-seq display, qPCR | Seuter et al., 2013a |
| HBEGF | Yes | ChIP-seq & FAIRE-seq display, qPCR | Seuter et al., 2013a |
| NFKBIA | Yes | ChIP-seq & FAIRE-seq display, qPCR | Seuter et al., 2013a |
| THBD | Yes | ChIP-seq & FAIRE-seq display, qPCR | Seuter et al., 2013a |
| IL1B | No | qPCR, microarray | Verway et al., 2013 |
| ASAP2 | Yes | ChIP-seq display, qPCR | Seuter et al., 2014b |
| YWHAQ | No | ChIP-seq display, qPCR | Seuter et al., 2014b |
| SEPT3 | Yes | ChIP-seq & FAIRE-seq display, qPCR | Seuter et al., 2014a |
| SFT2D1 | Yes | ChIP-seq & FAIRE-seq display, qPCR | Seuter et al., 2014a |
| SP100 | Yes | ChIP-seq & FAIRE-seq display, qPCR | Seuter et al., 2014a |
| ZFP36 | Yes | ChIP-seq & FAIRE-seq display, qPCR | Seuter et al., 2014a |
| TNF | – | qPCR | Reeves et al., 2014 |
| ASAP2 | Yes | ChIP-seq display | Tuoresmäki et al., 2014 |
| CAMP | Yes | ChIP-seq display | Tuoresmäki et al., 2014 |
| DENND6B | Yes | ChIP-seq display | Tuoresmäki et al., 2014 |
| NINJ1 | Yes | ChIP-seq display | Tuoresmäki et al., 2014 |
| PTGER3 | – | ChIP-seq display | Tuoresmäki et al., 2014 |
| SP100 | Yes | ChIP-seq display | Tuoresmäki et al., 2014 |
| TBP | No | ChIP-seq display | Tuoresmäki et al., 2014 |
| TRAK1 | Yes | ChIP-seq display | Tuoresmäki et al., 2014 |
| TLR10 | – | qPCR | Verma et al., 2014 |
| CD97 | Yes | ChIP-seq & FAIRE-seq display, qPCR | Wilfinger et al., 2014 |
| LRRC8A | Yes | ChIP-seq & FAIRE-seq display, qPCR | Wilfinger et al., 2014 |
| NRIP1 | Yes | ChIP-seq & FAIRE-seq display, qPCR | Wilfinger et al., 2014 |
| SLC37A2 | Yes | ChIP-seq & FAIRE-seq display, qPCR | Wilfinger et al., 2014 |
| TREM1 | Yes | qPCR | Hosoda et al., 2015 |
| BCL6 | Yes | Microarray, qPCR | Nurminen et al., 2015 |
| ELF4 | Yes | ChIP-seq & FAIRE-seq display, microarray, qPCR | Nurminen et al., 2015 |
| FUCA1 | Yes | ChIP-seq & FAIRE-seq display, microarray, qPCR | Nurminen et al., 2015 |
| ITGAM | Yes | ChIP-seq & FAIRE-seq display, microarray, qPCR | Nurminen et al., 2015 |
| LPGAT1 | No | ChIP-seq & FAIRE-seq display, microarray, qPCR | Nurminen et al., 2015 |
| LPP | – | Microarray, qPCR | Nurminen et al., 2015 |
| LRRC25 | Yes | ChIP-seq & FAIRE-seq display, microarray, qPCR | Nurminen et al., 2015 |
| NFE2 | Yes | ChIP-seq & FAIRE-seq display, microarray, qPCR | Nurminen et al., 2015 |
| POU4F2 | Yes | ChIP-seq & FAIRE-seq display, microarray, qPCR | Nurminen et al., 2015 |
| RTP4 | – | Microarray, qPCR | Nurminen et al., 2015 |
| SHE | Yes | ChIP-seq & FAIRE-seq display, microarray, qPCR | Nurminen et al., 2015 |
| SLC45A3 | No | ChIP-seq & FAIRE-seq display, microarray, qPCR | Nurminen et al., 2015 |
| TMEM243 | No | ChIP-seq & FAIRE-seq display, microarray, qPCR | Nurminen et al., 2015 |
| TREM1 | Yes | ChIP-seq & FAIRE-seq display, microarray, qPCR | Nurminen et al., 2015 |
| CD274 | Yes | ChIP-seq & FAIRE-seq display | Neme et al., 2016b |
| CYP26B1 | Yes | ChIP-seq & FAIRE-seq display | Neme et al., 2016b |
| EPB41L1 | No | ChIP-seq & FAIRE-seq display | Neme et al., 2016b |
| PLGRKT | No | ChIP-seq & FAIRE-seq display | Neme et al., 2016b |
| SIRT4 | Yes | ChIP-seq & FAIRE-seq display | Neme et al., 2016b |
| APBB3 | No | ChIP-seq & FAIRE-seq display | Neme et al., 2016a |
| CCL2 | Yes | ChIP-seq & FAIRE-seq display | Neme et al., 2016a |
| CD14 | Yes | ChIP-seq & FAIRE-seq display | Neme et al., 2016a |
| FCER2 | No | ChIP-seq & FAIRE-seq display | Neme et al., 2016a |
| HBEGF | Yes | ChIP-seq & FAIRE-seq display | Neme et al., 2016a |
| PFDN1 | Yes | ChIP-seq & FAIRE-seq display | Neme et al., 2016a |
| SLC35A4 | Yes | ChIP-seq & FAIRE-seq display | Neme et al., 2016a |
| SRA1 | Yes | ChIP-seq & FAIRE-seq display | Neme et al., 2016a |
| WDR55 | Yes | ChIP-seq & FAIRE-seq display | Neme et al., 2016a |
| ALOX5 | No | qPCR, RNA-seq | Seuter et al., 2016 |
| ASAP2 | Yes | qPCR, RNA-seq | Seuter et al., 2016 |
| CAMP | Yes | qPCR, RNA-seq | Seuter et al., 2016 |
| CD14 | Yes | qPCR, RNA-seq | Seuter et al., 2016 |
| ELL | Yes | qPCR, RNA-seq | Seuter et al., 2016 |
| FANCE | Yes | qPCR, RNA-seq | Seuter et al., 2016 |
| FBP1 | Yes | qPCR, RNA-seq | Seuter et al., 2016 |
| G0S2 | Yes | qPCR, RNA-seq | Seuter et al., 2016 |
| HBEGF | Yes | qPCR, RNA-seq | Seuter et al., 2016 |
| HTT | Yes | ChIP-seq & FAIRE-seq display, RNA-seq | Seuter et al., 2016 |
| MPC1 | No | qPCR, RNA-seq | Seuter et al., 2016 |
| MYC | – | qPCR, RNA-seq | Seuter et al., 2016 |
| NOD2 | Yes | ChIP-seq & FAIRE-seq display, RNA-seq | Seuter et al., 2016 |
| PPARGC1B | Yes | qPCR, RNA-seq | Seuter et al., 2016 |
| THBD | Yes | qPCR, RNA-seq | Seuter et al., 2016 |
| TMEM37 | Yes | qPCR, RNA-seq | Seuter et al., 2016 |
| ZFP36 | Yes | qPCR, RNA-seq | Seuter et al., 2016 |
| CYTH4 | Yes | ChIP-seq & FAIRE-seq display | Carlberg, 2017 |
| ELFN2 | Yes | ChIP-seq & FAIRE-seq display | Carlberg, 2017 |
| AKIRIN1 | Yes | ChIP-seq & FAIRE-seq display | Seuter et al., 2017a |
| BDH1 | No | ChIP-seq & FAIRE-seq display | Seuter et al., 2017a |
| CAMP | Yes | ChIP-seq & FAIRE-seq display | Seuter et al., 2017a |
| CD14 | Yes | ChIP-seq & FAIRE-seq display | Seuter et al., 2017a |
| CD226 | No | ChIP-seq & FAIRE-seq display | Seuter et al., 2017a |
| CD274 | Yes | ChIP-seq & FAIRE-seq display, qPCR | Seuter et al., 2017a |
| CD36 | Yes | qPCR | Seuter et al., 2017a |
| CD97 | Yes | ChIP-seq & FAIRE-seq display | Seuter et al., 2017a |
| DRAM1 | No | ChIP-seq & FAIRE-seq display | Seuter et al., 2017a |
| DUSP10 | Yes | ChIP-seq & FAIRE-seq display | Seuter et al., 2017a |
| FANCE | Yes | qPCR | Seuter et al., 2017a |
| FHL1 | No | ChIP-seq & FAIRE-seq display | Seuter et al., 2017a |
| MYO7B | No | ChIP-seq & FAIRE-seq display | Seuter et al., 2017a |
| PCTP | No | ChIP-seq & FAIRE-seq display | Seuter et al., 2017a |
| PPARGC1B | Yes | ChIP-seq & FAIRE-seq display | Seuter et al., 2017a |
| RTCB | – | ChIP-seq & FAIRE-seq display | Seuter et al., 2017a |
| SLC37A2 | Yes | ChIP-seq & FAIRE-seq display | Seuter et al., 2017a |
| SPI1 | – | qPCR | Seuter et al., 2017a |
| AGPAT1 | Yes | ChIP-seq & FAIRE-seq display | Carlberg, 2018 |
| CD14 | Yes | ChIP-seq & FAIRE-seq display | Nurminen et al., 2018 |
| CLMN | Yes | ChIP-seq & FAIRE-seq display | Nurminen et al., 2018 |
| TMEM37 | Yes | ChIP-seq & FAIRE-seq display | Nurminen et al., 2018 |
| CD14 | Yes | ChIP-seq & FAIRE-seq display | Seuter et al., 2018 |
| COQ3 | No | ChIP-seq & FAIRE-seq display | Seuter et al., 2018 |
| DND1 | Yes | ChIP-seq & FAIRE-seq display | Seuter et al., 2018 |
| NDUFA2 | No | ChIP-seq & FAIRE-seq display | Seuter et al., 2018 |
| PSMB1 | No | ChIP-seq & FAIRE-seq display | Seuter et al., 2018 |
| SLC25A15 | No | ChIP-seq & FAIRE-seq display | Seuter et al., 2018 |
| SLC52A2 | No | ChIP-seq & FAIRE-seq display | Seuter et al., 2018 |
| TBP | No | ChIP-seq & FAIRE-seq display | Seuter et al., 2018 |
| TMCO6 | Yes | ChIP-seq & FAIRE-seq display | Seuter et al., 2018 |
| WDR55 | Yes | ChIP-seq & FAIRE-seq display | Seuter et al., 2018 |
| ZNF44 | Yes | ChIP-seq & FAIRE-seq display | Seuter et al., 2018 |
| ACSL1 | Yes | ChIP-seq & FAIRE-seq display, RNA-seq | Nurminen et al., 2019 |
| CD14 | Yes | ChIP-seq & FAIRE-seq display, RNA-seq | Nurminen et al., 2019 |
| CDA | No | ChIP-seq & FAIRE-seq display, RNA-seq | Nurminen et al., 2019 |
| FBP1 | Yes | ChIP-seq & FAIRE-seq display, RNA-seq | Nurminen et al., 2019 |
| G0S2 | Yes | ChIP-seq & FAIRE-seq display, RNA-seq | Nurminen et al., 2019 |
| GLIPR1 | Yes | ChIP-seq & FAIRE-seq display, RNA-seq | Nurminen et al., 2019 |
| INSR | Yes | ChIP-seq & FAIRE-seq display, RNA-seq | Nurminen et al., 2019 |
| ITSN1 | Yes | ChIP-seq & FAIRE-seq display, RNA-seq | Nurminen et al., 2019 |
| KLHDC8B | No | ChIP-seq & FAIRE-seq display, RNA-seq | Nurminen et al., 2019 |
| NFKBIA | Yes | ChIP-seq & FAIRE-seq display, RNA-seq | Nurminen et al., 2019 |
| PNPLA1 | No | ChIP-seq & FAIRE-seq display, RNA-seq | Nurminen et al., 2019 |
| SERINC2 | Yes | ChIP-seq & FAIRE-seq display, RNA-seq | Nurminen et al., 2019 |
| SOAT1 | No | ChIP-seq & FAIRE-seq display, RNA-seq | Nurminen et al., 2019 |
| SSH1 | Yes | ChIP-seq & FAIRE-seq display, RNA-seq | Nurminen et al., 2019 |
List of 34 studies that investigated vitamin D target genes in undifferentiated THP-1 cells by the indicated types of assays. The information whether a gene is a primary target (yes), secondary target (no) or not detected (-) by a RNA-seq time course is derived from a re-analysis (Neme et al., 2017) of the original dataset from Seuter et al. (2016).