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. 2019 Mar 5;9:1156. doi: 10.3389/fphar.2018.01156

Box 2.

Medicines assigned to WHO access, watch, and reserve groups.

Access group

Medicine ATC code# Medicine ATC code#
Beta-lactam medicines Other antibacterials
Amoxicillin J01CA04 Amikacin J01GB06
Amoxicillin + clavulanic acid J01CR02 Azithromycin
Ampicillin J01CA01 Chloramphenicol J01BA01
Benzathine benzylpenicillin J01CE08 Ciprofloxacin
Benzylpenicillin J01CE01 Clarithromycin
Cefalexin J01DB01 Clindamycin J01FF01
Cefazolin J01DB04 Doxycycline J01AA02
Cefixime Gentamicin J01GB03
Cefotaxime Metronidazole J01XD01, P01AB01
Ceftriaxone Nitrofurantoin J01XE01
Cloxacillin J01CF02 Spectinomycin J01XX04
Phenoxymethylpenicillin J01CE02 Sulfamethoxazole + trimethoprim J01EE01
Piperacillin + tazobactam Vancomycin (oral and parenteral)
Procaine benzylpenicillin J01CE09

Watch group

Medicine ATC code

Quinolones and fluoroquinolones e.g., ciprofloxacin, levofloxacin, moxifloxacin, norfloxacin J01MA, J01MB
Third-generation cephalosporins (with or without beta-lactamase inhibitor) e.g., cefixime, ceftriaxone, cefotaxime, ceftazidime J01DD
Macrolides e.g., azithromycin, clarithromycin, erythromycin J01FA
Glycopeptides e.g., teicoplanin, vancomycin J01XA, A07AA09
Antipseudomonal penicillins with beta-lactamase inhibitor e.g., piperacillin + tazobactam J01CR03, J01CR05
Carbapenems e.g., meropenem, imipenem + cilastatin J01DH
Penems e.g., faropenem J01DI03

Reserve group

Medicine ATC code

Aztreonam J01DF01
Fourth-generation cephalosporins e.g., cefepime J01DE
Fifth-generation cephalosporins e.g., ceftaroline J01DI02, J01DI01, J01DI54
Fosfomycin IV J01XX01 (Only parenteral)
Oxazolidinone e.g., linezolid J01XX08, J01XX11
Polymyxins e.g., polymyxin B, colistin J01XB, A07AA10, A07AA05
Tigecycline J01AA12
Daptomycin J01XX09

Watch group antibiotics included in the EML/EMLc only for specific, limited indications; #ATC codes shown for medicines in the core access list – i.e., no overlap with Watch group antibiotics.

Medicines not specifically identified in the groups described form an “ungrouped” medicines category.