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. 2019 Mar 5;10:175. doi: 10.3389/fphar.2019.00175

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Copyright © 2019 Zhang, Liu, Zhang and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Trimetazidine suppressed EE-induced change in the expression of connexin 43 (CX43) in myocardial tissues of rats. The mRNA and protein level of CX43 was determined by real-time PCR (A), and western blot (B). The expression and distribution of CX43 in myocardial tissues were observed by immunofluorescence staining (C). Scale bar is 50 μm. Each value is shown as mean ±SD (n = 6). ^∗P < 0.05, ^∗∗P < 0.01, ^∗∗∗P < 0.001, versus the indicated group.