Table 1.
Clinical characteristics of the cases
| Case # | Histological subtype | Bone marrow involvement | Bulky mass | Ann Arbor stage | Age | Sex | IPS | First-line therapy | Response | Follow-up |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | MC | no | yes (mediastinal) | IIB | 23 | F | 0 | ABVD (x4) + Rt | CR + R | DOD (13 months) |
| 2 | NS | no | yes (mediastinal) | IIB | 31 | F | 4 | ABVD (x6) + Rt | CR + R | Alive (90 months) |
| 3 | MC | no | yes (retroperitoneal) | IIIB | 27 | M | 1 | ABVD (x6) | CR + R | Alive (64 months) |
| 4 | NS | NA | no | IIA | 40 | M | 2 | ABVD (x4) | CR + R | Alive (84 months) |
| 5 | NS | no | no | IIB | 41 | M | 2 | ABVD (x4) | PD | DOD (36 months) |
| 6 | NS | no | yes | IIB | 32 | F | 3 | ABVD (x6) + Rt | PD | DOD (10 months) |
| 7 | NS | no | no | IIB | 59 | M | 4 | ABVD (x6) | PD | DOD (7 months) |
| 8 | NS | yes | yes (mediastinal) | IV | 23 | F | 2 | ABVD (x6) + Rt | PD | AWD (42 months) |
| 9 | NS | no | no | IIIA | 42 | M | 2 | ABVD (x6) | PD | DOD (27 months) |
| 10 | MC | yes | no | IV | 21 | M | 5 | ABVD (x6) | PD | Lost |
| 11 | MC | yes | yes (abdominal) | IV | 69 | F | 3 | ABVD (x6) + Rt | CR + R | AWD (32 months) |
| 12 | NS | yes | no | IV | 73 | M | 4 | ABVD (x6) | PD | DOD (15 months) |
MC mixed cellularity, NS nodular sclerosis, IPS International Prognostic Score, ABVD adriamycin, bleomycin, vinblastine, and dacarbazine, Rt radiotherapy, CR + R complete remission and early relapse, PD progressive disease, DOD dead of disease, AWD alive with disease