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. 2019 Mar 11;10(3):236. doi: 10.1038/s41419-019-1487-3

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Representative images of immunofluorescence detection of NAA40 (green) on tissue microarrays containing a total of 318 normal and cancer colon tissues. Cell nuclei were visualized using DAPI staining (blue). Scale bar, 50 μm. b Graph showing the percentage of NAA40 positive and negative staining in normal adjacent tissues (n = 56), benign lesions (n = 30), and adenocarcinomas (n = 232). c Meta-analysis of NAA40 mRNA expression levels extracted from the TCGA data portal in 647 colorectal cancer (CRC; COAD, n = 480 and READ, n = 167) and 51 normal patient samples (colon normal, n = 41 and rectum normal, n = 10). The Mann–Whitney test was used for the statistical analysis (***p < 0.001)