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. 2019 Mar 11;9:4055. doi: 10.1038/s41598-019-40640-4

Table 2.

Structure-activity analysis of substituted phenol compounds.

Compound IC50 (μM) Estimated Vapor Pressure (mmHg at 25 °C) Boiling Point (degrees C)
graphic file with name 41598_2019_40640_IEq11_HTML.gif 15 ± 1 0.003 281.2
graphic file with name 41598_2019_40640_IEq12_HTML.gif 25 ± 3 0.01 247.7
graphic file with name 41598_2019_40640_IEq13_HTML.gif 32 ± 5 0.05 229.7
graphic file with name 41598_2019_40640_IEq14_HTML.gif 37 ± 7 0.003 261.4
graphic file with name 41598_2019_40640_IEq15_HTML.gif 50 ± 7 0.001 271.4
graphic file with name 41598_2019_40640_IEq16_HTML.gif 86 ± 17 0.008 247.7
graphic file with name 41598_2019_40640_IEq17_HTML.gif 92 ± 9 0.007 281.2
graphic file with name 41598_2019_40640_IEq18_HTML.gif 212 ± 29 0.02 229.6
graphic file with name 41598_2019_40640_IEq19_HTML.gif 261 ± 14 0.15 210.7

IC50 values for inhibition of Agam\Orco are presented as mean ± SEM (n = 3–9). Vapor pressures and boiling points were estimated as described in Methods.