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. 2019 Mar 11;9:4162. doi: 10.1038/s41598-019-39901-z

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

PRCC plots and corresponding effect on flow diagram for low levels of RdCVF. The two top panels, (A and B) are for 1 hour, the next two panels, (B and D), for 1 day, the next two panels, (E and F), for 7 days, and the two bottom panels, (G and H), are for 14 days. The left panels give the partial rank correlation coefficient (PRCC) plots for parameters with significant PRCC values while the right panels give the location of parameters with significant PRCC values in the flow diagram. The value of C is significantly lower compared to the healthy eye but levels off to a reduced value. The value of C and R_n at every time snapshot is given in each of the figures in the right panel. The PRCC values are given in Supplemental Information Table 17. See Sections 4.2 and 2.5 for details on PRCC analysis.