Table 3.
Putative epitopes of neuraminidase obtained from the peptide prediction analysis of the protein sequence (Brazil, 2018)
| Protein | HLA allele/haplotype | Peptide | Peptide sequence (15-mer) | Start | End |
|---|---|---|---|---|---|
| Neuraminidase (526 aa) |
DQA1*05:01/DQB1*03:01 | N1 | LMIFVGGVGLWQSTP | 268 | 282 |
| DQA1*05:01/DQB1*03:01 | N2 | RTTALSADSVAGRCF | 116 | 130 | |
| DQA1*05:01/DQB1*02:01 | N3 | DGTIGYFVEEDDEIS | 496 | 510 | |
| DQA1*05:01/DQB1*02:01 | N4 | SLVFIRFVLDDLFDA | 510 | 524 | |
| DQA1*01:02/DQB1*06:02 | N5 | VVFCCLMAMMHLSGQ | 17 | 31 | |
| DQA1*01:02/DQB1*06:02 | N6 | LKTANGTLIAMADRR | 199 | 213 | |
| DRB3*01:01 | N7 | YSDMTLLADGTIGYF | 488 | 502 | |
| DRB3*01:01 | N8 | PDYKGRVSYDSFPIS | 98 | 112 | |
| DRB4*01:01 | N9 | ALYLLVSDSLAVRDL | 83 | 97 | |
| DRB4*01:01 | N10 | LMAMMHLSGQEVTMW | 22 | 36 | |
| DRB5*01:01 | N11 | KQIRIGFSLPKETEE | 65 | 79 | |
| DRB5*01:01 | N12 | KTANGTLIAMADRRK | 200 | 214 | |
| DRB1*13:02 | N13 | IPSILKTANGTLIAM | 195 | 209 | |
| DRB1*13:02 | N14 | VALVQTQAGKLLMIF | 257 | 271 | |
| DRB1*15:01 | N15 | QAGKLLMIFVGGVGL | 263 | 277 | |
| DRB1*15:01 | N16 | PASRRLYREYEALFV | 170 | 184 | |
| DRB1*07:01 | N17 | FGDVALVQTQAGKLL | 254 | 268 | |
| DRB1*07:01 | N18 | YRIPSILKTANGTLI | 193 | 207 |
Start and end correspond to the positions in the protein sequence