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. 2019 Mar 5;13:92. doi: 10.3389/fnins.2019.00092

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Copyright © 2019 Kim, Han, Kim, Jung, Nam, Yoo, Hwang, Seong and Yoon.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of 4 weeks cold challenge on the expression levels of mRNA related to AHN, AHN-related signal transduction, and β-adrenergic receptor. Cold challenge for 4 weeks increases several genes related to (A) early growth response, (B) neuronal migration, (C) neuronal differentiation, (D) cell fate determination and other regulator of cell differentiation, (E) regulation of synaptic plasticity and synaptic transmission, (F) synaptogenesis and axonogenesis, (G) AHN-related to signaling transduction and (H) β-adrenergic receptor. ^∗ indicates a significant difference when compared to the CON group (p < 0.05); and ^∗∗ indicates a significant difference when compared with the CON group (p < 0.01). Data are shown as mean + SEM.