Table 3.
Effects of combined use of 2-deoxyglucose (2-DG) and metformin (MET) on proliferation of polycystic kidney epithelial cells
| 0 + 0 mM | 1.3 + 0.6 mM | 2.5 + 1.3 mM | 5 + 2.5 mM | 10 + 5 mM | |
|---|---|---|---|---|---|
| 12 h | 100.00 ± 2.18 | 85.92 ± 2.15*** | 73.47 ± 0.94*** | 68.16 ± 1.98*** | 58.40 ± 3.25*** |
| 24 h | 100.00 ± 3.21 | 80.02 ± 1.00*** | 68.83 ± 1.22*** | 56.53 ± 1.20*** | 43.21 ± 1.05*** |
| 36 h | 100.00 ± 1.97 | 73.43 ± 2.52*** | 63.98 ± 1.44*** | 55.11 ± 1.78*** | 40.31 ± 1.30*** |
| 48 h | 100.00 ± 2.43 | 67.02 ± 2.00*** | 56.41 ± 2.04*** | 44.87 ± 1.35*** | 35.81 ± 2.12*** |
*P < 0.05, **p < 0.01, ***p < 0.001 vs Control