Table 2.

Coefficients from the analysis of state fatigue prior to the N-Back task.

Coefficients for VAS-F (State) Fatigue and N-Back related activation
	Coefficients (p-value)
VAS-F Main effect
Postcentral Gyrus	−0.0102***
Middle Temporal Gyrus	−0.0184***
Superior Temporal Gyrus	−0.0104**
Superior Parietal Lobule	−0.0088**
Putamen	−0.0117***
Group Main effect	HC	GWI
Temporal Pole/Inferior Frontal Gyrus	−0.2780**	0.2540*
Superior Temporal Gyrus	−0.2560***	0.1210 ns
Middle Temporal Gyrus	−0.3790***	0.1520
Inferior Parietal Lobule (right)	0.2796***	−0.0701 ns
Inferior Parietal Lobule (left)	−0.3130*	0.4460*
Cuneus	−0.5120***	−0.0390 ns
Cerebellar Vermis	−0.2940***	0.2590*
Group × VAS-F Interaction
Inferior Frontal Gyrus	−0.0051***	0.0017 ns
Inferior Frontal Gyrus	−0.0099*	0.00001 ns
Caudate Nucleus	−0.0110**	0.0012 ns
Middle Temporal Gyrus	−0.0193***	0.00001 ns
Task × VAS-F Interaction	0-back	2-back
Caudate Tail	−0.0131***	0.0067 ns
Hippocampus	−0.0193***	0.0052 ns
Hippocampus	−0.0147***	0.0043 ns
Hippocampus	−0.0098*	0.0136***
Thalamus	−0.0145**	0.0098*
	HC		GWI
Group × Task Interaction	0-back	2-back	0-back	2-back
Middle Orbital Gyrus	−0.2720*	−0.2890*	0.1580 ns	−0.6370***
Middle Frontal Gyrus	−0.1560 ns	0.3990*	0.2120 ns	−0.1680 ns
Middle Frontal Gyrus	−0.3556*	0.4145*	0.0372 ns	−0.0032 ns
Inferior Frontal Gyrus	−0.1346	0.2140**	0.1356 ns	0.0129 ns
Caudate Nucleus	−0.1161	0.1779**	0.1109 ns	0.0093 ns
Calcarine Gyrus	−0.4630***	−0.0774 ns	0.0172 ns	−0.1372 ns
Thalamus	−0.2355**	0.1616*	0.0979 ns	−0.0288 ns
Group × Task × VAS-F Interaction
Caudate Tail	−0.0114*	0.0088*	0.0008 ns	−0.0013 ns
Hippocampus (right)	−0.0157***	0.0059*	0.0009 ns	−0.0015 ns
Hippocampus (left)	−0.0093**	0.0111**	0.0009 ns	−0.0009 ns

All significance tests relative to zero: ‘ns’ denotes not significant; ‘⋅’ p < 0.1; * p < 0.05; ** p < 0.01; *** p < 0.001.