Table 2.
Unadjusted mean volumes for each hippocampal subfield by participant group.
| Unadjusted mean volume (SD) (mm3) |
||||||
|---|---|---|---|---|---|---|
| HC |
tAD |
PCA |
||||
| L | R | L | R | L | R | |
| CA1 | 613 | 638 | 511 | 541 | 594 | 594 |
| (75) | (83) | (81) | (81) | (97) | (89) | |
| CA2/3 | 210 | 234 | 173 | 186 | 202 | 207 |
| (38) | (42) | (33) | (30) | (32) | (34) | |
| CA4 | 257 | 268 | 203 | 223 | 236 | 237 |
| (33) | (38) | (33) | (32) | (32) | (39) | |
| Pre-subiculum | 303 | 284 | 251 | 244 | 257 | 246 |
| (41) | (35) | (59) | (55) | (43) | (47) | |
| Subiculum | 423 | 432 | 341 | 352 | 381 | 364 |
| (51) | (48) | (58) | (56) | (57) | (46) | |
| Tail | 505 | 546 | 379 | 451 | 474 | 513 |
| (69) | (76) | (75) | (65) | (126) | (113) | |
| Para-subiculum | 61 | 57 | 52 | 51 | 54 | 55 |
| (13) | (10) | (15) | (18) | (19) | (19) | |
| GCMLDG | 298 | 309 | 234 | 253 | 265 | 266 |
| (38) | (42) | (41) | (39) | (36) | (42) | |
| Molecular layer | 557 | 571 | 447 | 463 | 509 | 496 |
| (63) | (68) | (76) | (67) | (71) | (68) | |
| HATA | 58 | 63 | 44 | 48 | 52 | 50 |
| (12) | (12) | (11) | (12) | (11) | (8) | |
| Total volume | 3370 | 3469 | 2687 | 2853 | 3077 | 3066 |
| (367) | (394) | (422) | (393) | (449) | (427) | |
Key: HC = Healthy controls; tAD = amnestic led typical Alzheimer's disease; PCA = posterior cortical atrophy; GCMLDG = Molecular and Granule Cell Layers of the Dentate Gyrus; HATA = Hippocampal Amygdala Transition Area; L = left; R = right.