Table 1.
Significant changes of metabolites before prep (Day 0), immediately after prep (Day 1), and 14 days after prep (Day14).
| Name | Day0 | Day1 | Day14 | Day0 vs Day1 | Day0 vs Day14 | Day1 vs Day14 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| median | min | max | median | min | max | median | min | max | p-value | q-value | p-value | q-value | p-value | q-value | |
| Ala | 2150.9 | 790.0 | 31602.1 | 18956.5 | 3482.8 | 37939.2 | 1948.3 | 490.9 | 39944.5 | 0.0078 | 0.1484 | 0.8438 | 1.0000 | 0.0547 | 0.2528 |
| Azelate | 94.7 | 43.3 | 206.0 | 50.5 | 17.2 | 86.4 | 82.6 | 43.3 | 106.0 | 0.0078 | 0.1484 | 0.4469 | 1.0000 | 0.0391 | 0.2143 |
| Betaine | 70.6 | 55.0 | 113.0 | 246.5 | 41.5 | 432.8 | 14.2 | 13.3 | 376.9 | 0.0156 | 0.2041 | 0.6721 | 1.0000 | 0.0078 | 0.0983 |
| Carnitine | 53.0 | 7.6 | 181.8 | 228.3 | 18.7 | 308.0 | 51.1 | 11.2 | 6859.7 | 0.0156 | 0.2041 | 0.5541 | 1.0000 | 0.2334 | 0.5741 |
| Choline | 75.3 | 19.8 | 1582.9 | 681.8 | 104.7 | 9623.0 | 96.3 | 26.4 | 344.6 | 0.0078 | 0.1484 | 0.4609 | 1.0000 | 0.0078 | 0.0983 |
| Citrulline | 143.0 | 45.6 | 752.2 | 975.9 | 123.0 | 1763.5 | 262.8 | 86.8 | 1127.1 | 0.0234 | 0.2333 | 0.0547 | 1.0000 | 0.0781 | 0.3154 |
| Cyclohexylamine | 1.9 | 0.9 | 3.8 | 0.9 | 0.8 | 1.3 | 1.9 | 1.0 | 4.0 | 0.0346 | 0.2634 | 0.7998 | 1.0000 | 0.0515 | 0.2528 |
| Gln | 547.4 | 255.3 | 2555.8 | 1679.4 | 554.3 | 5837.7 | 404.7 | 147.5 | 2187.5 | 0.0078 | 0.1484 | 0.1484 | 1.0000 | 0.0078 | 0.0983 |
| Glucuronate | 692.0 | 692.0 | 692.0 | 645.8 | 108.8 | 2866.0 | 449.2 | 57.3 | 841.1 | 0.0078 | 0.1484 | 0.3711 | 1.0000 | 0.0078 | 0.0983 |
| Glutarate | 2199.2 | 648.2 | 3054.6 | 519.2 | 102.7 | 2843.4 | 1451.8 | 408.9 | 4712.8 | 0.0391 | 0.2634 | 0.9453 | 1.0000 | 0.0156 | 0.1393 |
| Gly | 1109.2 | 370.7 | 39719.8 | 12856.5 | 1106.7 | 64448.3 | 1071.3 | 219.1 | 50755.4 | 0.0156 | 0.2041 | 0.8438 | 1.0000 | 0.0156 | 0.1393 |
| Guanidinoacetate | 81.1 | 7.7 | 93.3 | 76.2 | 53.5 | 2347.3 | 53.1 | 10.1 | 88.8 | 0.0391 | 0.2634 | 0.7874 | 1.0000 | 0.0360 | 0.2142 |
| Ile | 142.2 | 61.6 | 7647.9 | 6195.0 | 111.8 | 12163.1 | 131.4 | 64.9 | 8093.3 | 0.0078 | 0.1484 | 1.0000 | 1.0000 | 0.0078 | 0.0983 |
| Imidazole-4-acetate | 29.5 | 9.7 | 50.9 | 21.1 | 11.1 | 31.0 | 34.1 | 9.5 | 508.2 | 0.0360 | 0.2634 | 0.4469 | 1.0000 | 0.0225 | 0.1730 |
| Leu | 180.3 | 93.6 | 14887.6 | 13398.8 | 163.9 | 25732.8 | 209.1 | 125.2 | 17715.5 | 0.0156 | 0.2041 | 0.7422 | 1.0000 | 0.0078 | 0.0983 |
| Lys | 5216.9 | 1775.5 | 8243.1 | 11865.9 | 4083.9 | 51813.6 | 5674.0 | 1418.0 | 8843.3 | 0.0234 | 0.2333 | 1.0000 | 1.0000 | 0.1484 | 0.4125 |
| Malate | 142.3 | 34.8 | 461.1 | 750.5 | 158.8 | 2190.6 | 137.6 | 57.6 | 320.7 | 0.0078 | 0.1484 | 0.8885 | 1.0000 | 0.0078 | 0.0983 |
| Met | 94.2 | 41.4 | 2503.8 | 884.8 | 47.2 | 5156.0 | 84.1 | 49.1 | 3570.7 | 0.0391 | 0.2634 | 0.9453 | 1.0000 | 0.0391 | 0.2143 |
| Methionine sulfoxide | 73.0 | 25.6 | 314.7 | 259.8 | 54.6 | 534.5 | 75.4 | 24.2 | 549.3 | 0.0494 | 0.3226 | 0.5469 | 1.0000 | 0.4609 | 0.7417 |
| N-Methylalanine | 14.8 | 10.9 | 26.2 | 12.9 | 6.4 | 14.5 | 21.9 | 6.6 | 30.6 | 0.0140 | 0.2041 | 0.3125 | 1.0000 | 0.0078 | 0.0983 |
| o-Acetylcarnitine | 20.5 | 13.0 | 35.0 | 61.3 | 16.2 | 323.6 | 2538.7 | 2538.7 | 2538.7 | 0.0360 | 0.2634 | 1.0000 | 1.0000 | 0.4017 | 0.7104 |
| Ornithine | 258.6 | 63.9 | 1927.6 | 2239.6 | 261.3 | 5614.7 | 194.9 | 45.4 | 2067.2 | 0.0078 | 0.1484 | 0.5469 | 1.0000 | 0.0234 | 0.1730 |
| Phe | 113.1 | 38.3 | 11390.1 | 6958.7 | 105.1 | 15807.2 | 100.4 | 65.0 | 14544.1 | 0.0225 | 0.2333 | 0.6740 | 1.0000 | 0.0547 | 0.2528 |
| Pimelate | 210.5 | 32.8 | 421.1 | 207.5 | 184.2 | 262.1 | 151.2 | 35.0 | 441.3 | 0.0234 | 0.2333 | 0.8438 | 1.0000 | 0.0156 | 0.1393 |
| Pipecolate | 399.4 | 63.5 | 877.5 | 44.2 | 15.7 | 181.4 | 477.9 | 60.4 | 1064.6 | 0.0078 | 0.1484 | 0.7422 | 1.0000 | 0.0078 | 0.0983 |
| Succinate | 1756.9 | 966.1 | 46418.6 | 50951.9 | 1014.5 | 96369.9 | 1562.0 | 438.7 | 79882.2 | 0.0391 | 0.2634 | 0.9453 | 1.0000 | 0.0391 | 0.2143 |
| Trp | 113.6 | 51.5 | 3164.5 | 688.0 | 65.7 | 3358.1 | 91.8 | 37.1 | 7998.4 | 0.0234 | 0.2333 | 0.9453 | 1.0000 | 0.3125 | 0.6621 |
| Tyr | 560.4 | 201.5 | 15741.2 | 5126.9 | 329.6 | 16119.8 | 445.9 | 157.2 | 18964.3 | 0.0391 | 0.2634 | 0.9453 | 1.0000 | 0.0781 | 0.3154 |
| Val | 422.7 | 203.3 | 20646.0 | 13500.5 | 336.1 | 24902.8 | 452.7 | 212.4 | 23332.0 | 0.0078 | 0.1484 | 0.9453 | 1.0000 | 0.0078 | 0.0983 |
| 2-Hydroxybutyrate | 487.4 | 304.9 | 669.9 | 707.4 | 185.7 | 1483.0 | 352.3 | 85.7 | 619.0 | 0.0360 | 0.2634 | 0.7893 | 1.0000 | 0.0346 | 0.2142 |
| 3-Hydroxybutyrate | 259.8 | 152.4 | 735.7 | 635.9 | 252.4 | 1633.6 | 185.9 | 101.7 | 693.9 | 0.0078 | 0.1484 | 0.1056 | 1.0000 | 0.0078 | 0.0983 |
| 5-Aminolevulinate | 15.5 | 9.6 | 23.5 | 12.5 | 9.9 | 17.5 | 15.5 | 8.2 | 24.4 | 0.0346 | 0.2634 | 0.2476 | 1.0000 | 0.2041 | 0.5138 |
Note. mol per 1 g of human feces (nmol/g), SD, standard deviation, NA, not applicable.