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. 2019 Jan 15;47(5):2349–2364. doi: 10.1093/nar/gky1317

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© The Author(s) 2019. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 7. — KDM3A promotes colon cancer through hippo pathway. (A, B) The data sets of colorectal cancer were downloaded from TCGA database. Boxplots show the expression (FPKM) of KDM3A (A) and YAP1 (B) in cancer and normal tissues. (C–E) The correlation of KDM3A with YAP1(C) and hippo target genes, WEE1 (D) and BBC3 (E), in colon adenocarcinoma. (F) The patient survival curves with high- or low-expressed KDM3A in colon adenocarcinoma. (G) A sketch to illustrate the role of KDM3A in hippo pathway and enhancer activation. All the above cancer-related data were downloaded from TCGA.