Table 4.
Brain responses of patients and controls to pictures of children.
| Brain region | BA | k | Side | MNI coordinates |
T | Pcorrected | ||
|---|---|---|---|---|---|---|---|---|
| x | y | z | ||||||
| Undressed > Dressed | ||||||||
| Patients | ||||||||
| Inf. Temporal Gyr. (SVC+) | 37 | 331 | R | 50 | −68 | −8 | 4.81 | <0.001 |
| Middle Occipital Gyr. | 19 | 159 | L | −40 | −88 | 0 | 4.59 | <0.05 |
| Controls | ||||||||
| Middle Occipital Gyr.a, (SVC+) | 18 | 162 | R | 24 | −98 | 2 | 4.77 | <0.05 |
| Fusiform Gyr. a, SVC- | 18 | 66 | L | −22 | −90 | −18 | 4.21 | <.05SVC |
| Undressed > Dressed: Controls – Patients | ||||||||
| Inferior Temporal Gyr. | 20 | 146 | R | 58 | −34 | −16 | 3.86 | <0.05 |
| Dressed > Undressed | ||||||||
| Patients | ||||||||
| Lingual Gyr. | 18 | 172 | R | 2 | −70 | 0 | 4.45 | <0.05 |
| Controls | ||||||||
| Superior Frontal Gyr. | 6 | 557 | R | 18 | −14 | 72 | 5.15 | <0.001 |
| Paracentral Lobule | 5 | 212 | L | −4 | −42 | 64 | 4.75 | <0.01 |
| Postcentral Gyr. | 43 | 176 | L | −64 | −6 | 24 | 4.04 | <0.05 |
Note. Contrast 1: ChUndressed – ChDressed. All probabilities are corrected for multiple comparisons, based on the Family-Wise Error (FWE) rate control. Pcorrected refers to cluster-wise significance (cluster-forming threshold: 0.001, unc.; cluster-extent thresholds: for (Undressed – Dressed), FWEc = 159 for patients and FWEc = 162 for controls; for (Dressed – Undressed), FWEc = 172 for patients and FWEc = 176 for controls; for between-groups analysis, FWEc = 146). k: Cluster-size; SVC+, SVC- Small Volume Correction, based on areas showing activation or deactivation, respectively, in response to VSSa in healthy males; (SVC+) Region identified both within whole mask and with small volume correction; for these regions, unless otherwise noted, Pcorr refers to analysis in whole mask. Gyr.: gyrus; BA: Brodmann area.
Cluster that survives exclusive masking by regions activated in response to images of nude adults (exploratory analysis).