Table 1.
The clinical characteristics of PHPT patients at baseline.
| PTH | Total |
Tertile 1 |
Tertile 2 |
Tertile 3 |
Correlation between PTH and clinical index |
|
|---|---|---|---|---|---|---|
| N = 496 | <196 pg/ml |
196–465.1 pg/ml |
>465.1 pg/ml |
β | P | |
| N = 165 | N = 165 | N = 166 | ||||
| Age | 54 (46,61.5) | 56 (50, 63) | 54 (46,62) | 51 (41, 59)⁎ | −0.06 | <0.0001 |
| Male/Female (%) | 145/351 (29.2/70.8) | 37/128 (22.4/77.6) | 49/116 (29.7/70.3) | 59/107 (35.5/64.5)⁎ | / | / |
| Duration (months) | 5 (1,24) | 6 (2,36) | 4.5 (1,24) | 6 (1,24) | −0.07 | 0.47 |
| Body weight (kg) | 60 (52,68) | 61 (55,69) | 60 (53, 69) | 57 (49, 65)⁎ | −0.03 | <0.0001 |
| BMI (kg/m2) | 22.4 (20.3,24.9) | 22.9 (20.8,25.4) | 23.0 (20.6, 25.1) | 21.9 (19.3, 24.2)⁎ | −0.04 | <0.0001 |
| Calcium (mmol/l) | 2.77 (2.56,3.01) | 2.57 (2.44,2.70) | 2.75 (2.58, 2.92)⁎ | 3.11 (2.87,3.36)⁎ | 0.08 | <0.0001 |
| Phosphorus (mmol/l) | 0.84 (0.70,0.99) | 0.98 (0.86, 1.09) | 0.85 (0.74, 0.94)⁎ | 0.72 (0.60, 0.82)⁎ | −0.14 | <0.0001 |
| 25 (OH)D (nmol/l) | 27.0 (15.3, 37.9) | 31.5 (17.8,43.8) | 26.0 (14.5, 35.5)⁎ | 23.3 (14.2, 33.1)⁎ | −0.08 | 0.02 |
| Scr (μmol/l) | 68 (56, 85) | 63 (55, 73) | 68 (54, 82) | 82 (60, 119)⁎ | 0.12 | <0.0001 |
| Albumin (g/l) | 38 (35,40) | 38 (36,41) | 38 (36,40) | 37 (34,40)⁎ | −0.03 | <0.0001 |
| BMDL1-4 (g/cm2) | 0.92 (0.79,1.05) | 0.98 (0.87,1.09) | 0.95 (0.81, 1.07) | 0.85 (0.75,1.00)⁎ | −0.08 | <0.0001 |
| BMD total hip (g/cm2) | 0.78 (0.68,0.89) | 0.83 (0.73,0.94) | 0.80 (0.71, 0.89) | 0.70 (0.60,0.82)⁎ | −0.11 | <0.0001 |
Values are shown as median (interquartile range) or N (%); Scr: serum creatinine; BMD: Bone mineral density; L1-4: lumbar 1–4.
⁎
P < .05 vs. PTH tertile 1.