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. 2018 Dec 26;40:517–527. doi: 10.1016/j.ebiom.2018.12.035

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© 2018 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 1 — B cell subset distribution. (A) Sampling timepoints, divided into two groups of 5 and 18 SLE patients by date of data generation. (B) t-distributed stochastic neighbour embedding (t-SNE) clustering of B cells from 18 SLE patients and all follow-up occasions (100 cells per sample). (C–D) Distribution of naïve (purple) and memory (green) B cells in the SLE patients (all follow-up occasions; B) and a healthy control (C). (E) A predominant CD57 and CD11c expression in two distinct clusters (upper right and upper left) is apparent. (F) The CD57⁺ cluster is absent in the healthy control. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)