Supplementary Fig. S1.

a–c. Clonogenic forming ability under serial doses of ASC-J9^®. 14 days result in C4-2 (a), CWR22Rv-1 (b), and SV-HUC (c) cells after 6 h ASC-J9^® treatment; Supplementary Fig. S2: Protein level of total ATR and total CHK1 change after IR. (a) total ATR (b) total CHK1; Supplementary Fig. S3: ASC-J9^® treatment has partially effect in AR negative PCa cells. Clonogenic assay result of PC-3 cells; Supp Fig. S4: ROS levels in PCa and normal bladder cells. DCF-DA value in same numbers of C4–2 and SV-HUC cells before and after IR.