Table 3.

Restricted mean survival (RMS) time ratio between low- and high-IPSOV groups in different data sets.

Dataset	NLow-IPSOV	NHigh-IPSOV	RMSLow-IPSOV (95%CI)a	RMSHigh-IPSOV (95%CI)a	RMS ratio (95%CI)b	P
Training set	258	258	57.58 (52.61–62.55)	42.73 (39.02–46.45)	1.35 (1.19–1.52)	<0.001
Validation set 1	196	213	84.51 (72.62–96.41)	61.82 (52.53–71.11)	1.37 (1.11–1.67)	0.003
Validation set 2	185	412	60.52 (54.77–66.28)	46.40 (42.95–49.84)	1.31 (1.15–1.47)	<0.001
Validation set 3	413	223	92.42 (83.49–101.35)	60.77 (51.99–69.56)	1.52 (1.27–1.81)	<0.001
Validation set 4	179	236	70.18 (60.61–79.75)	37.17 (31.17–43.18)	1.88 (1.52–2.33)	<0.001
Validation set 5	109	85	40.50 (37.80–43.20)	32.75 (29.00–36.51)	1.24 (1.08–1.41)	0.002

^aRMS time: months.

^bRMS ratio = RMS_Low-IPSOV/ RMS_High-IPSOV.