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. 2019 Mar 5;10:208. doi: 10.3389/fphys.2019.00208

FIGURE 9.

FIGURE 9

Gene expression of hypertrophy markers NPPA and NPPB in sheep 3 days post-MI: Mean normalized expression (MNE) of NPPA (A) and NPPB (B) in Sham, and Remote, Border, and Infarct Tissue. Superscript letters (Fetal Sheep; a, b, c and Adolescent Sheep; x, y, z) represent significance between tissue regions (Remote, Border, and Infarct) at each age (P < 0.05). represents significantly different data from the sham animals at each age (P < 0.05). Analyses between tissue regions (Infarct vs. Border vs. Remote) at each age were assessed using a nested Analysis of variance (ANOVA). A Bonferroni post hoc test was performed with multiple comparisons for each tissue region against the Sham tissue. n = 5 per treatment group per age.