Skip to main content
. 2019 Feb 13;47(5):2190–2204. doi: 10.1093/nar/gkz059

Figure 2.

Figure 2.

(A) Cartoon representation of superimposed c-MYC Pu22 G-quadruplex structures in apo state (brown, model 1 in the NMR structure, PDB 1xav) and with quindoline (purple, model 1 in the NMR structure, PDB 2l7v). The two quindoline molecules are shown in cyan. (B) Superimposed structures without ligands. (C) Connolly surface of c-MYC Pu22 G-quadruplex structure from PDB 2l7v. The red spheres highlight the central platform on top of 3′ end G-quartet and at the bottom of 5′ end G-quartet, while green, yellow and blue spheres represent the locations of grooves connecting to the central platform, respectively.