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Cortical and subcortical regions associated with the phenomenological features of TS. Tic genesis and expression (green) is associated with premotor cortex, SMA, insula, M1, S1, the putamen, globus pallidus, and thalamus; premonitory sensations (blue) with the SMA, insula, M1, S1, and the putamen; tic suppression (red) with the inferior frontal gyrus, preSMA, and the subthalamic nucleus.
