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. 2019 Jan 3;40:643–654. doi: 10.1016/j.ebiom.2018.12.059

Fig. 6.

Fig. 6

STF-083010 suppress the inflammasome signaling and pyroptosis after SCI and OGD-induced neuron.

(A) The protein expression of p-IRE1 in spinal cord at 3 days after SCI. (B) Double immunofluorescence of cleaved-caspase1 and NeuN in sections from tissue at 3 days after SCI (bar: 50 μm). (C—F) The protein expression of GSDMD, cleaved-caspase1, cleaved-caspase11, IL-1β, IL-18, NLRP1 and NLRP3 in spinal cord at 3 days after SCI. (G) and (H) The protein expression of p-IRE1, IRE1, cleaved-caspase1, IL-1β, NLRP1 and NLRP3 in neuron treated as above. All data represent mean ± S.D. (n = 5). **P < .01.