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. 2019 Feb 25;11(2):483. doi: 10.3390/nu11020483

Figure 6.

Figure 6

Ergosterol inhibited the renal transforming growth factor-β1 (TGF-β1)/ drosophila mothers against decapentaplegic 2 (Smad2) signaling pathway in STZ-induced diabetic mice. This figure shows these results of Western blot analysis of TGF-β1, Smad2, phosphor-Smad2, Smad4, and Smad7. NC: normal control; DN: diabetic nephropathy model induced by STZ; ERG10, ERG20, ERG40: 10, 20, 40 mg/kg/day ergosterol administration. Data are presented as the means ± SD, n = 3. ** p < 0.01, *** p < 0.001 compared with NC; # p < 0.05, ## p < 0.001 compared with DN.