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Experimental Groups for FSD Surgery
| Experimental group at 8 weeks | Animals, n | Scaffold volume, μL | Total dose |
|
|---|---|---|---|---|
| BMP2, μg (600 μg/mL) | shRNA lentivirus, pfu (1 × 107 pfu/mL) | |||
| PBS (control) | 5 | 3.5 | 0 | 0 |
| BMP2 | 5 | 3.5 | 2.1 | 0 |
| BMP2 + shControl | 5 | 3.5 | 2.1 | 35,000 |
| BMP2 + shPPARγ | 5 | 3.5 | 2.1 | 35,000 |
FSD, femoral segmental defect; pfu, plaque-forming unit.
