ALI |
acute lung injury |
AM |
alveolar macrophages |
ARDS |
acute respiratory distress syndrome |
ATI cells |
alveolar epithelial type I cells |
ATII cells |
alveolar epithelial type II cells |
COPD |
chronic obstructive pulmonary disease |
DPPC |
dipalmitoylphosphatidylcholine |
ICAM-1 |
intercellular Adhesion Molecule 1 |
IFN- β |
interferon β |
IFN- γ |
interferon γ |
IL |
interleukin |
IL-1R |
interleukin-1 receptor |
IPF |
idiopathic pulmonary fibrosis |
LBP |
LPS-binding protein |
Mal |
MyD88 adaptor-like protein |
mCD14 |
membrane-bound CD14 |
MCP-1 |
monocyte chemoattractant protein 1 |
MD2 |
myeloid differentiation protein 2 |
MIP-3α |
macrophage inflammatory protein 3α |
MyD88 |
myeloid differentiation factor 88 |
NF- κB |
nuclear factor-κB |
NO |
nitric oxide |
PAMP |
pathogen-associated molecular pattern |
PPRs |
pattern-recognition receptors |
RAGE |
receptor for advanced glycation end products |
RNS |
reactive nitrogen species |
ROS |
reactive oxygen species |
sCD14 |
Soluble CD14 |
SIRPα |
Signal regulatory protein α |
SP-A |
surfactant protein A |
SP-B |
surfactant protein B |
SP-C |
surfactant protein C |
SP-D |
surfactant protein D |
SPs |
surfactant proteins |
sRAGE |
soluble isoform of receptor for advanced glycation end products |
TGF-β |
transforming growth factor β |
TIR domains |
Toll/IL-1R homology domains |
TLRs |
toll-like receptors |
TNF- α |
tumor necrosis factor α |
TRAM |
TRIF-related adaptor molecule |
TRIF |
TIR-domain-containing adaptor protein |
VCAM-1 |
vascular cell adhesion molecule 1 |