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. 2019 Feb 1;10(2):104. doi: 10.3390/mi10020104

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Biophysical property analysis of single-cells by using microfluidics. (a) A dynamic fluidic control system that enables the buoyant mass of cells as small as bacteria and as large as mammalian lymphocytes to be repeatedly measured with a suspended microchannel resonator (SMR). Adapted by permission from Reference [119], copyright Nature Publishing Group 2010. (b) A microfluidic device that can simultaneously characterize the mechanical and electrical properties of individual biological cells in a high-throughput manner (>1000 cells/min). Adapted by permission from Reference [127], copyright American Chemical Society 2018.