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. 2019 Feb 22;20(4):966. doi: 10.3390/ijms20040966

Figure 4.

Figure 4

BCAS2 acts together with AF-2 coactivators to increase ERα activity. (A) Luciferase assays were carried out with pcDNA-BCAS2 or empty vector (EV), transfected with and without coactivators SRC-1, CBP or TIF2 and treated in the absence (EtOH) or presence of 10 nM of E2 or 100 nM of TAM in MCF7 cells. Similar assays were carried out in MDA-MB-231 (B) and SK-BR-3 (C) cells with the addition of transfected pSG5-ER Statistical analysis was carried out using one-way ANOVA with Bonferroni posttest; * p < 0.01, ** p < 0.005, *** p < 0.001.