Effect of Sophora tomentosa extract (25 mg/kg, 50 mg/kg, and 100 mg/kg, po) on (A) rearing count and (B) rearing time on an open field test in an MPTP-induced PD mouse model. Data are expressed as mean ± SEM (n = 10). * p < 0.05, ** p < 0.01, *** p < 0.001, compared with the MPTP group. Sophora tomentosa was administered for 15 consecutive days until the behavioral tests. MPTP (20 mg/kg, intraperitoneal) were given two times at four-hour intervals daily for five days until behavioral tests. MPTP: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, PD: Parkinson’s disease, ST: Sophora tomentosa.