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. 2019 Feb 14;41(4):2181–2193. doi: 10.3892/or.2019.7013

Figure 2.

Figure 2.

Phototoxic effect of e6-PDT in T24 and 5637 MCTSs. (A and B) Morphological changes of T24 and 5637 MCTSs were recorded using an inverted microscope at 24 h post-e6-PDT. MCTSs in the e6-PDT group exhibited destruction of spheroid structure and density reduction. Scale bar=100 µm. (C and D) Cell viability of T24 and 5637 MCTSs was determined by the CellTiter-Glo assay (n=3). **P<0.01 and ***P<0.001 vs. blank control group. e6-PDT, chlorophyllin e6-mediated photodynamic therapy; MCTSs, multicellular tumor spheroids.