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Inhibition/binding affinity constants (Ki) for inhibition of recombinant human MAO-A and MAO-B by acacetin, acacetin 7-methyl ether, and deprenyl.
| Compounds | Monoamine Oxidase-B | |
|---|---|---|
| Ki (nM) * | Type of Inhibition | |
| Acacetin 7-methyl ether | 45.0 ± 3.0 | Competitive/Partially Reversible |
| Acacetin | 36 ± 4.0 | Competitive/Reversible |
| Deprenyl | 29 ± 6.3 | Mixed/Irreversible |
* Values are mean ± S.D. of triplicate experiments.
