Table I.
Cell lines treated with Bepridil in the CMap and L1000 FWD databases.
| Database | Mean score | Cell line | Dose (µm) | Score | n | P-value |
|---|---|---|---|---|---|---|
| CMap | −0.659 | 4 | 0.071 | |||
| MCF7 | 10 | −0.677 | 2 | 0.101 | ||
| PC3 | 10 | −0.756 | 1 | – | ||
| HL60 | 10 | −0.525 | 1 | – | ||
| L1000FWD | −0.0167 | 2 | – | |||
| HCC515 | 10 | N/A | 1 | 0.001 | ||
| VCaP | 10 | N/A | 1 | 0.002 |
CMap, Connectivity Map; L1000FWD, L1000 Fireworks Display; MCF7, human breast cancer cell line; PC3, human prostate cancer cell line; HL60, human leukemia cell line; HCC515, human lung adenocarcinoma cell line; VCaP, human prostate cancer cell line; N, number of cell lines.