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Effect of PRFR on HepG2 cells cycle arrest. The cells were incubated with or without various concentrations (0–40 µg/mL) of PRFR for 48 h. Cell cycle arrest was determined using Guava Cell cycle analysis (a). All assays were performed in triplicate and the mean ± standard deviations are shown as the histogram (b). ** p < 0.01 and **** p < 0.0001 versus the control.
