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. 2019 Feb 25;41(4):2226–2240. doi: 10.3892/or.2019.7030

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Copyright: © Huang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 8. — Detection of the effects of miR-146a-5p and TCSF on lung cancer A549 cell viability, proliferation and apoptosis. Cell viability was determined by (A) CellTiter-Blue and (B) Hoechst 33342. (C) Cell proliferation was analyzed using an MTS kit. Cell apoptosis was assessed via (D) Caspaes3/7 assays and (E) Hoechst 33342. (F) The knockout effect of TCSF siRNA at different time points. *P<0.05, **P<0.01 and ***P<0.001 vs. scrambled siRNA. miR, microRNA; TCSF, tumor collagenase stimulatory factor; siRNA, small interfering RNA.