Table 3.
Study characteristics regarding Anti-nuclear auto-antibodies.
| Studies | Type of Study | Type of Auto-Antibodies | Study Group | Control Group | Clinical Pregnancy Rate | Live Birth/Ongoing Pregnancy Rate | Miscarriage Rate | |||
|---|---|---|---|---|---|---|---|---|---|---|
| Study Group | Control Group | Study Group | Control Group | Study Group | Control Group | |||||
| Chen et al., 2017 [11] | Prospective | −ANA | −178 ANA(+) Women | −844 ANA(-) Women | 55.60% | 61% | 50.56% | 55.90% | 9.10% | 8.30% |
| Fan et al., 2017 [76] | Not provided | −ANA −Anti-dsDNA |
−52 ANA(+) and Anti-dsDNA(+) Women −86 ANA(+) and Anti-dsDNA(−) Women |
-121 ANA(−) and Anti-dsDNA(−) Women | 11.5% 30.2% |
47.10% | 0% 18.6% |
36.30% | 100% 38.5% |
22.80% |
| Li et al., 2015 [77] | Not provided | −ANA | −204 ANA(+) Women | -313 ANA(+) Women | 27.72% | 45.03% | 21.78% | 43.50% | 21.43% | 3.39% |
| Ying et al., 2013 [79] | Retrospective | −ANA −ACA |
−20 ANA(+) and ACA(+) Women −51 ANA(+) and ACA(-) Women |
−116 ANA(−) and ACA(−) Women | 25% 35.3% |
53.40 | n/a | n/a | n/a | n/a |
| Zhu et al., 2013 [80] | Retrospective | −ANA | −66 ANA(+) Women | −233 ANA(−) Women | 17.30% | 56.50% | 9.61% | 51.10% | 44.40% | 9.62% |
| Ying et al., 2013 [78] | Not provided | −ANA | −50 ANA(+) Women | −50 ANA (−) Women | 28% | 52% | n/a | n/a | n/a | n/a |
| Ying et al., 2012 [68] | Not provided | −ANA | −66 ANA(+) Women | −233 ANA(−) Women | 28.10% | 46.40% | n/a | n/a | n/a a | n/a a |
a: In Ying et al., 2012 study miscarriage rates was provided per gestational sacks, thus, information on miscarriages per clinical pregnancy could not be extracted.