Table 1.
Demographic and clinical screening measures for PD patients and controls ON and OFF medication.
| Group | PD | Control | p-value | |
|---|---|---|---|---|
| n | 24 | 18 | ||
| Age | 68.12 (1.10) | 66.06 (2.12) | 0.355 | |
| Education | 15.94 (0.62) | 15.76 (1.09) | 0.877 | |
| Age of Onset | 61.64 (1.39) | |||
| Duration | 6.48 (0.74) | – | ||
| LED | 600.32 (59.32) | – | ||
| DA | 11 | – | ||
| H & Y | 2.52 (0.02) | – | ||
| UPDRS-III | OFF | 19.03 (1.00) | 0.15 (0.12) | <0.001 |
| ON | 16.03 (1.06) | – | ||
| BDI-II | OFF | 8.09 (1.16) | 2.44 (0.70) | 0.001 |
| ON | 8.33 (1.31) | 2.50 (0.67) | 0.001 | |
| BAI-I | OFF | 7.38 (1.48) | 1.72 (0.48) | 0.003 |
| ON | 8.19 (1.59) | 2.61 (0.54) | 0.006 | |
| ANART | 123.57 (1.45) | 123.90 (1.80) | 0.892 | |
| MOCA | 27.40 (0.32) | 28.22 (0.37) | 0.123 |
Values are reported as mean (±SEM). P-values measure the significance of the between group differences in each relevant category. LED = ι-dopa equivalence dose (mg/daily); DA = Number of individuals prescribed a dopamine agonist; H & Y = Hoehn and Yahr scale score; UPDRS-III = Unified Parkinson's Disease Rating Scale – Motor sub-scale; BDI-II = Beck Depression Inventory II; BAI-I = Beck Anxiety Inventory I; ANART = American Adult National Reading Test estimate of verbal IQ; MOCA = Montreal Cognitive Assessment. Patients with PD completed the ANART and MOCA on medication regardless of medication order.