Table 1.
The measurement of body weight, feeding behavior, and urine secretion in loperamide (Lop)-induced constipated Sprague Dawley (SD) rats.
| Contents | NCTR | SPA | Lop | ||
|---|---|---|---|---|---|
| Vehicle | SPA | ||||
| Body weight (g) | 289 ± 17 | 288 ± 7 | 279 ± 11 | 283 ± 12 | |
| Feeding behavior | Food intake (g/day) | 18.7 ± 3.6 | 23.0 ± 1.2 | 22.0 ± 3.28 | 23.8 ± 1.8 |
| Water consumption (ml/day) | 29.4 ± 3.4 | 27.7 ± 3.4 | 26.1 ± 4.1 | 25.4 ± 3.6 | |
| Urine volume (mL/day) | 11.6 ± 5.6 | 18.3 ± 2.1 * | 21.6 ± 2.8 * | 16.0 ± 1.6 # | |
Seven rats per group were used in all contents, and each parameter was assayed in triplicate in each test. The data are reported as the mean ± SD. * p < 0.05 compared to the non-constipation (CNTR) group. # p < 0.05 compared to the Lop + Vehicle-treated group. SPA; saponin-enriched A. cochinchinesis extract.