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Compounds 1a (A) and 3 (C) exerted antiproliferative effect on SH-SY5Y cells exposed to increasing concentration of synthesized compounds for 24, 48, and 72 h. No antiproliferative effect was observed for compound 2a (B). Each value is the mean ± S.E.M. of three experiments performed eight times. **** p < 0.0001, *** p < 0.001, ** p < 0.01, * p < 0.05 vs. CTRL.
