Table 4.
Adipose tissue mRNA related to inflammatory and metabolic pathways of LDLr-KO mice fed experimental diets for 16 weeks.
| PUFA | PALM | PALM INTER | STEAR | STEAR INTER | |
|---|---|---|---|---|---|
| Tnf/b2m | 1.35 ± 0.26 | 1.29 ± 0.14 | 1.10 ± 0.19 | 1.14 ± 0.18 | 0.97 ± 0.09 |
| Acrp30/b2m | 0.86 ± 0.08 | 0.74 ± 0.05 | 0.61 ± 0.07 | 0.80 ± 0.12 | 0.76 ± 0.08 |
| Plin/b2m | 0.42 ± 0.07 | 0.47 ± 0.04 | 0.39 ± 0.03 | 0.41 ± 0.07 | 0.46 ± 0.04 |
| Pnpla2/b2m | 0.80 ± 0.16 b | 1.28 ± 0.11 a | 0.74 ± 0.08 b | 1.02 ± 0.20 b | 0.89 ± 0.16 b |
| Lipe/b2m | 0.58 ± 0.12 | 0.70 ± 0.03 | 0.62 ± 0.06 | 0.59 ± 0.08 | 0.55 ± 0.06 |
| Scd1/b2m | 0.89 ± 0.27 b | 1.60 ± 0.30 a,b | 1.59 ± 0.83 a,b | 1.99 ± 0.40 a | 2.21 ± 0.98 a |
Adipose tissue samples were dissected from LDLr-KO mice fed a high-fat diet enriched with polyunsaturated fatty acids (PUFA), palmitic acid (PALM), palmitic interesterified fat (INTER PALM), stearic acid (STEAR), and stearic interesterified fat (INTER STEAR) for 16 weeks. Results were standardized to beta-2-microglobulin (b2m) and normalized to the expression of adipose samples from mice fed a diet containing 7% of energy as fat. Data were checked for normality prior to statistical analysis. One-way ANOVA was performed, followed by the post hoc Newman–Keuls Multiple Comparison Test. Statistically significant difference is represented by different letters (p < 0.05) with a > b values. Data presented as mean ± SD (n = 5–7).