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Optic nerve pathology in the Asah1P361R/P361R mice. A–F: Light micrograph of hematoxylin and eosin (H&E), Luxol fast blue (LFB), and Mac-2–stained optic nerve sections from 8- to 9-week–old Asah1+/+ and Asah1P361R/P361R mice. G and H: Immunofluorescence staining for glial fibrillary acidic protein (GFAP), ionized calcium-binding adapter molecule 1 (Iba1), and DAPI on optic nerves of 8- to 9-week–old Asah1+/+ and Asah1P361R/P361R mice. Scale bars: 100 μm (A–F); 50 μm (G and H).
