Table 3.
List of proteins identified in medicinal cannabis apical buds and trichomes by bottom-up proteomics.
| Protein Annotation | Abbreviation | Uniprot Accession or Patent Number | Species | Length (AA) | Number of Peptides Identified | EC Number | Function | Pathway |
|---|---|---|---|---|---|---|---|---|
| Small auxin upregulated protein | SAUR03 | A0A172J1 × 8 | Boehmeria nivea | 93 | 1 | response to auxin | Phytohormone response | |
| Small auxin upregulated protein | SAUR20 | A0A172J1Z7 | Boehmeria nivea | 147 | 1 | response to auxin | Phytohormone response | |
| Small auxin upregulated protein | SAUR23 | A0A172J212 | Boehmeria nivea | 99 | 1 | response to auxin | Phytohormone response | |
| Small auxin upregulated protein | SAUR24 | A0A172J211 | Boehmeria nivea | 102 | 1 | response to auxin | Phytohormone response | |
| Small auxin upregulated protein | SAUR28 | A0A172J206 | Boehmeria nivea | 108 | 1 | response to auxin | Phytohormone response | |
| Small auxin upregulated protein | SAUR30 | A0A172J210 | Boehmeria nivea | 100 | 1 | response to auxin | Phytohormone response | |
| Small auxin upregulated protein | SAUR31 | A0A172J276 | Boehmeria nivea | 152 | 1 | response to auxin | Phytohormone response | |
| Small auxin upregulated protein | SAUR40 | A0A172J219 | Boehmeria nivea | 105 | 1 | response to auxin | Phytohormone response | |
| Small auxin upregulated protein | SAUR44 | A0A172J227 | Boehmeria nivea | 152 | 4 | response to auxin | Phytohormone response | |
| Small auxin upregulated protein | SAUR48 | A0A172J226 | Boehmeria nivea | 133 | 1 | response to auxin | Phytohormone response | |
| Small auxin upregulated protein | SAUR54 | A0A172J237 | Boehmeria nivea | 118 | 5 | response to auxin | Phytohormone response | |
| Small auxin upregulated protein | SAUR55 | A0A172J229 | Boehmeria nivea | 97 | 3 | response to auxin | Phytohormone response | |
| Small auxin upregulated protein | SAUR58 | A0A172J236 | Boehmeria nivea | 97 | 1 | response to auxin | Phytohormone response | |
| Small auxin upregulated protein | SAUR59 | A0A172J243 | Boehmeria nivea | 106 | 5 | response to auxin | Phytohormone response | |
| Small auxin upregulated protein | SAUR60 | A0A172J238 | Boehmeria nivea | 105 | 1 | response to auxin | Phytohormone response | |
| Small auxin upregulated protein | SAUR70 | A0A172J249 | Boehmeria nivea | 183 | 1 | response to auxin | Phytohormone response | |
| Small auxin upregulated protein | SAUR71 | A0A172J2A4 | Boehmeria nivea | 183 | 1 | response to auxin | Phytohormone response | |
| Small auxin upregulated protein | SAUR51 | A0A172J290 | Boehmeria nivea | 97 | 1 | response to auxin | Phytohormone response | |
| Small auxin upregulated protein | SAUR52 | A0A172J241 | Boehmeria nivea | 149 | 1 | response to auxin | Phytohormone response | |
| Cannabidiolic acid synthase | CBDAS | A6P6V9 | Cannabis sativa | 544 | 8 | 1.21.3.8 | oxidative cyclisation of CBGA, producing CBDA | Cannabinoid biosynthesis |
| Geranylpyrophosphate:olivetolate geranyltransferase | GOT | WO 2011/017798 Al | Cannabis sativa | 395 | 4 | alkylation of OLA with geranyldiphosphate to form CBGA | Cannabinoid biosynthesis | |
| Olivetolic acid cyclase | OAC | I1V0C9 | Cannabis sativa | 545 | 1 | 4.4.1.26 | functions in concert with OLS/TKS to form OLA | Cannabinoid biosynthesis |
| Olivetolic acid cyclase | OAC | I6WU39 | Cannabis sativa | 101 | 5 | 4.4.1.26 | functions in concert with OLS/TKS to form OLA | Cannabinoid biosynthesis |
| 3,5,7-trioxododecanoyl-CoA synthase | OLS | B1Q2B6 | Cannabis sativa | 385 | 7 | 2.3.1.206 | olivetol biosynthesis | Cannabinoid biosynthesis |
| Tetrahydrocannabinolic acid synthase | THCAS | A0A0H3UZT7 | Cannabis sativa | 325 | 1 | 1.21.3.7 | oxidative cyclisation of CBGA, producing THCA | Cannabinoid biosynthesis |
| Tetrahydrocannabinolic acid synthase | THCAS | Q33DP7 | Cannabis sativa | 545 | 1 | 1.21.3.7 | oxidative cyclisation of CBGA, producing THCA | Cannabinoid biosynthesis |
| Tetrahydrocannabinolic acid synthase | THCAS | Q8GTB6 | Cannabis sativa | 545 | 4 | 1.21.3.7 | oxidative cyclisation of CBGA, producing THCA | Cannabinoid biosynthesis |
| Putative kinesin heavy chain | kin | Q5TIP9 | Cannabis sativa | 145 | 1 | microtubule-based movement | Cytoskeleton | |
| Betv1-like protein | Betv1 | I6XT51 | Cannabis sativa | 161 | 38 | Defence response | ||
| ATP synthase subunit alpha | atp1 | A0A0M5M1Z3 | Cannabis sativa | 509 | 12 | Produces ATP from ADP | Energy metabolism | |
| ATP synthase subunit alpha | atp1 | E5DK51 | Cannabis sativa | 349 | 1 | Produces ATP from ADP | Energy metabolism | |
| ATP synthase subunit 4 | atp4 | A0A0M4S8F3 | Cannabis sativa | 198 | 7 | Produces ATP from ADP | Energy metabolism | |
| ATP synthase subunit alpha | atpA | A0A0C5ARX6 | Cannabis sativa | 507 | 9 | Produces ATP from ADP | Energy metabolism | |
| ATP synthase subunit beta | atpB | F8TR83 | Cannabis sativa | 413 | 1 | 3.6.3.14 | Produces ATP from ADP | Energy metabolism |
| ATP synthase CF1 epsilon subunit | atpE | A0A0C5AUH9 | Cannabis sativa | 133 | 1 | Produces ATP from ADP | Energy metabolism | |
| ATP synthase subunit beta, chloroplastic | atpF | A0A0C5AUE9 | Cannabis sativa | 189 | 2 | Component of the F(0) channel | Energy metabolism | |
| NADH-ubiquinone oxidoreductase chain 1 | nad1 | A0A0M4S8G1 | Cannabis sativa | 324 | 1 | 7.1.1.2 | Energy metabolism | |
| NADH-ubiquinone oxidoreductase chain 5 | nad5 | A0A0M4RVP1 | Cannabis sativa | 669 | 1 | 7.1.1.2 | Energy metabolism | |
| NADH dehydrogenase subunit 7 | nad7 | A0A0M4S7M8 | Cannabis sativa | 394 | 1 | 7.1.1.2 | Energy metabolism | |
| NADH dehydrogenase subunit 9 | nad9 | A0A0M4R4N3 | Cannabis sativa | 190 | 2 | 7.1.1.2 | Energy metabolism | |
| NADH dehydrogenase subunit 7 | nadhd7 | A0A0X8GLG5 | Cannabis sativa | 394 | 1 | Energy metabolism | ||
| NADH-quinone oxidoreductase subunit H | ndhA | A0A0C5APZ2 | Cannabis sativa | 363 | 1 | 1.6.5.11 | NDH-1 shuttles electrons from NADH to quinones | Energy metabolism |
| NADH-quinone oxidoreductase subunit N | ndhB | A0A0C5B2K5 | Cannabis sativa | 510 | 1 | 1.6.5.11 | NDH-1 shuttles electrons from NADH to quinones | Energy metabolism |
| NADH-quinone oxidoreductase subunit K | ndhE | A0A0C5AUJ8 | Cannabis sativa | 101 | 4 | 1.6.5.11 | NDH-1 shuttles electrons from NADH to quinones | Energy metabolism |
| NADH-quinone oxidoreductase subunit C | ndhJ | A0A0C5B2I2 | Cannabis sativa | 158 | 2 | 1.6.5.11 | NDH-1 shuttles electrons from NADH to quinones | Energy metabolism |
| 1-deoxy-D-xylulose-5-phosphate reductoisomerase | DXR | A0A1V0QSG8 | Cannabis sativa | 472 | 2 | Converts 2-C-methyl-D-erythritol 4P into 1-deoxy-D-xylulose 5P | Isoprenoid biosynthesis | |
| Transferase FPPS1 | FPPS1 | A0A1V0QSH0 | Cannabis sativa | 341 | 1 | Isoprenoid biosynthesis | ||
| Transferase FPPS2 | FPPS2 | A0A1V0QSH7 | Cannabis sativa | 340 | 3 | Isoprenoid biosynthesis | ||
| Transferase GPPS large subunit | GPPS | A0A1V0QSH4 | Cannabis sativa | 393 | 2 | Isoprenoid biosynthesis | ||
| Transferase GPPS small subunit | GPPS | A0A1V0QSG9 | Cannabis sativa | 326 | 1 | Isoprenoid biosynthesis | ||
| Transferase GPPS small subunit2 | GPPS | A0A1V0QSI1 | Cannabis sativa | 278 | 1 | Isoprenoid biosynthesis | ||
| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase | HDR | A0A1V0QSH9 | Cannabis sativa | 408 | 6 | Converts (E)-4-hydroxy-3-methylbut-2-en-1-yl-2P into isopentenyl-2P | Isoprenoid biosynthesis | |
| Isopentenyl-diphosphate delta-isomerase | IDI | A0A1V0QSG5 | Cannabis sativa | 304 | 7 | Converts isopentenyl diphosphate into dimethylallyl diphosphate | Isoprenoid biosynthesis | |
| Mevalonate kinase | MK | A0A1V0QSI0 | Cannabis sativa | 416 | 3 | 2.7.1.36 | Converts (R)-mevalonate into (R)-5-phosphomevalonate | Isoprenoid biosynthesis |
| Diphosphomevalonate decarboxylase | MPDC | A0A1V0QSG4 | Cannabis sativa | 455 | 4 | Isoprenoid biosynthesis | ||
| Phosphomevalonate kinase | PMK | A0A1V0QSH8 | Cannabis sativa | 486 | 4 | Converts (R)-5-phosphomevalonate into (R)-5-diphosphomevalonate | Isoprenoid biosynthesis | |
| Non-specific lipid-transfer protein | ltp | P86838 | Cannabis sativa | 20 | 3 | transfer lipids across membranes | Lipid biosynthesis | |
| Non-specific lipid-transfer protein | ltp | W0U0V5 | Cannabis sativa | 91 | 9 | transfer lipids across membranes | Lipid biosynthesis | |
| 4-coumarate:CoA ligase | 4CL | A0A142EGJ1 | Cannabis sativa | 544 | 1 | 6.2.1.12 | forms 4-coumaroyl-CoA from 4-coumarate | Phenylpropanoid biosynthesis |
| 4-coumarate:CoA ligase | 4CL | V5KXG5 | Cannabis sativa | 550 | 3 | 6.2.1.12 | forms 4-coumaroyl-CoA from 4-coumarate | Phenylpropanoid biosynthesis |
| Phenylalanine ammonia-lyase | PAL | V5KWZ6 | Cannabis sativa | 707 | 4 | 4.3.1.24 | Catalyses L-phenylalanine = trans-cinnamate + ammonia | Phenylpropanoid biosynthesis |
| NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic | ndhF | A0A0C5AUJ6 | Cannabis sativa | 755 | 1 | 1.6.5.- | NDH shuttles electrons from NAD(P)H:plastoquinone to quinones | Photosynthesis |
| Photosystem I P700 chlorophyll a apoprotein A1 | pasA | A0A0U2DTB0 | Cannabis sativa | 750 | 2 | 1.97.1.12 | bind P700, the primary electron donor of PSI | Photosynthesis |
| Photosystem I P700 chlorophyll a apoprotein A2 | psaB | A0A0C5APY0 | Cannabis sativa | 734 | 2 | 1.97.1.12 | bind P700, the primary electron donor of PSI | Photosynthesis |
| Photosystem I iron-sulfur center | psaC | A0A0C5AS17 | Cannabis sativa | 81 | 10 | 1.97.1.12 | assembly of the PSI complex | Photosynthesis |
| Photosystem II CP47 reaction center protein | psbB | A9XV91 | Cannabis sativa | 488 | 1 | binds chlorophyll in PSII | Photosynthesis | |
| Ribulose bisphosphate carboxylase large chain | rbcL | A0A0B4SX31 | Cannabis sativa | 312 | 15 | 4.1.1.39 | carboxylation of D-ribulose 1,5-bisphosphate | Photosynthesis |
| Small ubiquitin-related modifier | smt3 | Q5TIQ0 | Cannabis sativa | 76 | 2 | protein sumoylation | Protein metabolism | |
| Cytochrome c biogenesis FC | ccmFc | A0A0M4RVN1 | Cannabis sativa | 447 | 1 | Mitochondrial electron carrier protein | Respiration | |
| Cytochrome c biogenesis FN | ccmFn | A0A0M3UM18 | Cannabis sativa | 575 | 2 | Mitochondrial electron carrier protein | Respiration | |
| Cytochrome c biogenesis protein CcsA | ccsA | A0A0C5B2L0 | Cannabis sativa | 320 | 1 | biogenesis of c-type cytochromes | Respiration | |
| Cytochrome c | cytC | P00053 | Cannabis sativa | 111 | 2 | Mitochondrial electron carrier protein | Respiration | |
| 7S vicilin-like protein | Cs7S | A0A219D1T7 | Cannabis sativa | 493 | 2 | nutrient reservoir activity | Storage | |
| Edestin 1 | ede1D | A0A090CXP5 | Cannabis sativa | 511 | 1 | Seed storage protein | Storage | |
| 4-(cytidine 5’-diphospho)-2-C-methyl-D-erythritol kinase | CMK | A0A1V0QSI2 | Cannabis sativa | 408 | 4 | Adds 2-phosphate to 4-CDP-2-C-methyl-d-erythritol | Terpenoid biosynthesis | |
| 1-deoxy-D-xylulose-5-phosphate synthase | DXPS1 | A0A1V0QSH6 | Cannabis sativa | 730 | 2 | Converts d-glyceraldehyde 3P into 1-deoxy-d-xylulose 5P | Terpenoid biosynthesis | |
| 1-deoxy-D-xylulose-5-phosphate synthase | DXS2 | A0A1V0QSH5 | Cannabis sativa | 606 | 5 | Converts d-glyceraldehyde 3P into 1-deoxy-d-xylulose 5P | Terpenoid biosynthesis | |
| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase | HDS | A0A1V0QSG3 | Cannabis sativa | 748 | 3 | Converts (E)-4-hydroxy-3-methylbut-2-en-1-yl-2P into 2-C-methyl-d-erythritol 2,4-cyclo-2P | Terpenoid biosynthesis | |
| 3-hydroxy-3-methylglutaryl coenzyme A reductase | hmgR | A0A1V0QSF5 | Cannabis sativa | 588 | 5 | 1.1.1.34 | synthesizes (R)-mevalonate from acetyl-CoA | Terpenoid biosynthesis |
| 3-hydroxy-3-methylglutaryl coenzyme A reductase | hmgR | A0A1V0QSG7 | Cannabis sativa | 572 | 2 | 1.1.1.34 | synthesizes (R)-mevalonate from acetyl-CoA | Terpenoid biosynthesis |
| Terpene synthase | TPS | A0A1V0QSF2 | Cannabis sativa | 567 | 1 | formation of cyclic terpenes through the cyclisation of linear terpenes | Terpenoid biosynthesis | |
| Terpene synthase | TPS | A0A1V0QSF3 | Cannabis sativa | 551 | 3 | formation of cyclic terpenes through the cyclisation of linear terpenes | Terpenoid biosynthesis | |
| Terpene synthase | TPS | A0A1V0QSF4 | Cannabis sativa | 613 | 1 | formation of cyclic terpenes through the cyclisation of linear terpenes | Terpenoid biosynthesis | |
| Terpene synthase | TPS | A0A1V0QSF6 | Cannabis sativa | 551 | 1 | formation of cyclic terpenes through the cyclisation of linear terpenes | Terpenoid biosynthesis | |
| Terpene synthase | TPS | A0A1V0QSF8 | Cannabis sativa | 629 | 2 | formation of cyclic terpenes through the cyclisation of linear terpenes | Terpenoid biosynthesis | |
| Terpene synthase | TPS | A0A1V0QSF9 | Cannabis sativa | 624 | 2 | formation of cyclic terpenes through the cyclisation of linear terpenes | Terpenoid biosynthesis | |
| Terpene synthase | TPS | A0A1V0QSG0 | Cannabis sativa | 573 | 1 | formation of cyclic terpenes through the cyclisation of linear terpenes | Terpenoid biosynthesis | |
| Terpene synthase | TPS | A0A1V0QSG1 | Cannabis sativa | 640 | 1 | formation of cyclic terpenes through the cyclisation of linear terpenes | Terpenoid biosynthesis | |
| Terpene synthase | TPS | A0A1V0QSG6 | Cannabis sativa | 556 | 3 | formation of cyclic terpenes through the cyclisation of linear terpenes | Terpenoid biosynthesis | |
| Terpene synthase | TPS | A0A1V0QSH1 | Cannabis sativa | 594 | 1 | formation of cyclic terpenes through the cyclisation of linear terpenes | Terpenoid biosynthesis | |
| (-)-limonene synthase, chloroplastic | TPS1 | A7IZZ1 | Cannabis sativa | 622 | 2 | 4.2.3.16 | monoterpene (C10) olefins biosynthesis | Terpenoid biosynthesis |
| Maturase K | matK | A0A1V0IS32 | Cannabis sativa | 509 | 1 | assists in splicing its own and other chloroplast group II intron | Transcription | |
| Maturase K | matK | Q95BY0 | Cannabis sativa | 507 | 2 | assists in splicing its own and other chloroplast group II intron | Transcription | |
| Maturase R | matR | A0A0M5M254 | Cannabis sativa | 651 | 1 | assists in splicing introns | Transcription | |
| DNA-directed RNA polymerase subunit beta | rpoB | A0A0C5ARQ8 | Cannabis sativa | 1070 | 3 | 2.7.7.6 | transcription of DNA into RNA | Transcription |
| DNA-directed RNA polymerase subunit beta | rpoB | A0A0C5ARX9 | Cannabis sativa | 1393 | 4 | 2.7.7.6 | transcription of DNA into RNA | Transcription |
| DNA-directed RNA polymerase subunit beta | rpoB | A0A0U2H5U7 | Cannabis sativa | 1070 | 1 | 2.7.7.6 | transcription of DNA into RNA | Transcription |
| DNA-directed RNA polymerase subunit beta | rpoC1 | A0A0C5AUF5 | Cannabis sativa | 683 | 6 | 2.7.7.6 | transcription of DNA into RNA | Transcription |
| DNA-directed RNA polymerase subunit beta | rpoC2 | A0A0H3W6G1 | Cannabis sativa | 1389 | 1 | 2.7.7.6 | transcription of DNA into RNA | Transcription |
| DNA-directed RNA polymerase subunit beta | rpoC2 | A0A0X8GKF1 | Cannabis sativa | 1391 | 1 | 2.7.7.6 | transcription of DNA into RNA | Transcription |
| DNA-directed RNA polymerase subunit beta | rpoC2 | A0A1V0IS28 | Cannabis sativa | 1393 | 1 | 2.7.7.7 | transcription of DNA into RNA | Transcription |
| Ribosomal protein L14 | rpl14 | A0A0C5AS10 | Cannabis sativa | 122 | 2 | assembly of the ribosome | Protein metabolism | |
| 50S ribosomal protein L16, chloroplastic | rpl16 | A0A0C5AUJ2 | Cannabis sativa | 119 | 2 | assembly of the 50S ribosomal subunit | Protein metabolism | |
| Ribosomal protein L2 | rpl2 | A0A0M3ULW5 | Cannabis sativa | 337 | 2 | assembly of the ribosome | Protein metabolism | |
| 50S ribosomal protein L20 | rpl20 | A0A0C5B2J3 | Cannabis sativa | 120 | 1 | Binds directly to 23S rRNA to assemble the 50S ribosomal subunit | Protein metabolism | |
| Ribosomal protein S11 | rps11 | A0A0C5ART4 | Cannabis sativa | 138 | 1 | assembly of the ribosome | Protein metabolism | |
| 30S ribosomal protein S12, chloroplastic | rps12 | A0A0C5APY5 | Cannabis sativa | 132 | 1 | translational accuracy | Protein metabolism | |
| 30S ribosomal protein S12, chloroplastic | rps12 | A0A0C5B2L8 | Cannabis sativa | 125 | 1 | translational accuracy | Protein metabolism | |
| Ribosomal protein S13 | rps13 | A0A0M5M201 | Cannabis sativa | 116 | 1 | assembly of the ribosome | Protein metabolism | |
| Ribosomal protein S19 | rps19 | A0A0M3ULW7 | Cannabis sativa | 94 | 1 | assembly of the ribosome | Protein metabolism | |
| Ribosomal protein S2 | rps2 | A0A0C5APX8 | Cannabis sativa | 236 | 1 | assembly of the ribosome | Protein metabolism | |
| 30S ribosomal protein S3, chloroplastic | rps3 | A0A0C5ART6 | Cannabis sativa | 155 | 3 | assembly of the 30S ribosomal subunit | Protein metabolism | |
| Ribosomal protein S3 | rps3 | A0A0M3UM22 | Cannabis sativa | 548 | 1 | assembly of the ribosome | Protein metabolism | |
| Ribosomal protein S3 | rps3 | A0A110BC84 | Cannabis sativa | 548 | 1 | assembly of the ribosome | Protein metabolism | |
| Ribosomal protein S4 | rps4 | A0A0M4RG21 | Cannabis sativa | 352 | 1 | assembly of the ribosome | Protein metabolism | |
| Ribosomal protein S7 | rps7 | A0A0C5ARU3 | Cannabis sativa | 155 | 2 | assembly of the ribosome | Protein metabolism | |
| Ribosomal protein S7 | rps7 | A0A0M4R6T5 | Cannabis sativa | 148 | 1 | assembly of the ribosome | Protein metabolism | |
| Protein TIC 214 | ycf1 | A0A0C5AS14 | Cannabis sativa | 356 | 2 | protein precursor import into chloroplasts | Protein metabolism | |
| Protein TIC 214 | ycf1 | A0A0H3W815 | Cannabis sativa | 1878 | 21 | protein precursor import into chloroplasts | Protein metabolism | |
| Acyl-activating enzyme 1 | aae1 | H9A1V3 | Cannabis sativa | 720 | 1 | Unknown | ||
| Acyl-activating enzyme 10 | aae10 | H9A1W2 | Cannabis sativa | 564 | 1 | Unknown | ||
| Acyl-activating enzyme 12 | aae12 | H9A8L1 | Cannabis sativa | 757 | 2 | Unknown | ||
| Acyl-activating enzyme 13 | aae13 | H9A8L2 | Cannabis sativa | 715 | 3 | Unknown | ||
| Acyl-activating enzyme 2 | aae2 | H9A1V4 | Cannabis sativa | 662 | 3 | Unknown | ||
| Acyl-activating enzyme 3 | aae3 | H9A1V5 | Cannabis sativa | 543 | 7 | Unknown | ||
| Acyl-activating enzyme 4 | aae4 | H9A1V6 | Cannabis sativa | 723 | 3 | Unknown | ||
| Acyl-activating enzyme 5 | aae5 | H9A1V7 | Cannabis sativa | 575 | 1 | Unknown | ||
| Acyl-activating enzyme 6 | aae6 | H9A1V8 | Cannabis sativa | 569 | 1 | Unknown | ||
| Acyl-activating enzyme 8 | aae8 | H9A1W0 | Cannabis sativa | 526 | 3 | Unknown | ||
| Cannabidiolic acid synthase-like 2 | CBDAS3 | A6P6W1 | Cannabis sativa | 545 | 1 | Has no cannabidiolic acid synthase activity | Unknown | |
| Putative LOV domain-containing protein | LOV | A0A126WVX7 | Cannabis sativa | 664 | 8 | Unknown | ||
| Putative LOV domain-containing protein | LOV | A0A126WVX8 | Cannabis sativa | 1063 | 7 | Unknown | ||
| Putative LOV domain-containing protein | LOV | A0A126WZD3 | Cannabis sativa | 574 | 1 | Unknown | ||
| Putative LOV domain-containing protein | LOV | A0A126X0M1 | Cannabis sativa | 725 | 4 | Unknown | ||
| Putative LOV domain-containing protein | LOV | A0A126X1H2 | Cannabis sativa | 910 | 6 | Unknown | ||
| Putative LysM domain containing receptor kinase | lyk2 | U6EFF4 | Cannabis sativa | 599 | 1 | Unknown | ||
| Uncharacterised protein | unknown | A0A1V0IS79 | Cannabis sativa | 1525 | 2 | Unknown | ||
| Uncharacterised protein | unknown | L0N5C8 | Cannabis sativa | 543 | 1 | Unknown | ||
| Protein Ycf2 | ycf2 | A0A0C5APZ4 | Cannabis sativa | 2302 | 9 | ATPase of unknown function | Unknown | |
| Protein translocase subunit | secA | A0A0N9ZJA6 | Cannabis sativa | 158 | 7 | Binds ATP | Protein metabolism | |
| ATP synthase subunit beta, chloroplastic | atpB | A0A0U2DTF2 | Cannabis sativa subsp. sativa | 498 | 20 | 3.6.3.14 | Produces ATP from ADP | Energy metabolism |
| Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic | accD | A0A0U2DTG7 | Cannabis sativa subsp. sativa | 497 | 3 | 2.1.3.15 | acetyl coenzyme A carboxylase complex | Lipid biosynthesis |
| NAD(P)H-quinone oxidoreductase subunit K, chloroplastic | ndhK | A0A0U2DTF9 | Cannabis sativa subsp. sativa | 226 | 1 | 1.6.5.- | NDH shuttles electrons from NAD(P)H:plastoquinone to quinones | Photosynthesis |
| Cytochrome f | petA | A0A0U2DW83 | Cannabis sativa subsp. sativa | 320 | 1 | mediates electron transfer between PSII and PSI | Photosynthesis | |
| Photosystem II protein D1 | psbA | A0A0U2DTE4 | Cannabis sativa subsp. sativa | 353 | 2 | 1.10.3.9 | assembly of the PSII complex | Photosynthesis |
| Photosystem II CP43 reaction center protein | psbC | A0A0U2DTE2 | Cannabis sativa subsp. sativa | 473 | 5 | core complex of PSII | Photosynthesis | |
| Photosystem II D2 protein | psbD | A0A0U2DVP6 | Cannabis sativa subsp. sativa | 353 | 3 | 1.10.3.9 | assembly of the PSII complex | Photosynthesis |
| Cytochrome b559 subunit alpha | psbE | A0A0U2DTH9 | Cannabis sativa subsp. sativa | 83 | 2 | reaction center of PSII | Photosynthesis | |
| Ribulose bisphosphate carboxylase large chain | rbcL | A0A0U2DW50 | Cannabis sativa subsp. sativa | 475 | 13 | 4.1.1.39 | carboxylation of D-ribulose 1,5-bisphosphate | Photosynthesis |
| Photosystem I assembly protein Ycf4 | ycf4 | A0A0U2DVM4 | Cannabis sativa subsp. sativa | 184 | 1 | assembly of the PSI complex | Photosynthesis | |
| 30S ribosomal protein S14, chloroplastic | rps14 | A0A0U2DTI4 | Cannabis sativa subsp. sativa | 100 | 2 | Binds 16S rRNA, required for the assembly of 30S particles | Protein metabolism | |
| 30S ribosomal protein S15, chloroplastic | rps15 | A0A0U2DW79 | Cannabis sativa subsp. sativa | 90 | 1 | assembly of the 30S ribosomal subunit | Protein metabolism | |
| ATP synthase subunit beta, chloroplastic | atpB | A0A0U2H0U7 | Humulus lupulus | 498 | 2 | 3.6.3.14 | Produces ATP from ADP | Energy metabolism |
| ATP synthase subunit beta, chloroplastic | atpB | A0A0U2H587 | Humulus lupulus | 191 | 1 | Component of the F(0) channel | Energy metabolism | |
| NAD(P)H-quinone oxidoreductase subunit I, chloroplastic | ndhI | A0A0U2GY49 | Humulus lupulus | 171 | 2 | 1.6.5.- | NDH shuttles electrons from NAD(P)H:plastoquinone to quinones | Photosynthesis |
| DNA-directed RNA polymerase subunit beta | rpoC2 | A0A0U2H146 | Humulus lupulus | 1398 | 1 | 2.7.7.6 | transcription of DNA into RNA | Transcription |
| 50S ribosomal protein L20, chloroplastic | rpl20 | A0A0U2H0V8 | Humulus lupulus | 120 | 1 | Binds directly to 23S rRNA to assemble the 50S ribosomal subunit | Protein metabolism | |
| 30S ribosomal protein S4, chloroplastic | rps4 | A0A0U2H5A0 | Humulus lupulus | 202 | 1 | binds directly to 16S rRNA to assemble the 30S subunit | Protein metabolism | |
| 30S ribosomal protein S8, chloroplastic | rps8 | A0A0U2GZU5 | Humulus lupulus | 134 | 2 | binds directly to 16S rRNA to assemble the 30S subunit | Protein metabolism | |
| Protein Ycf2 | ycf2 | A0A0U2H6B6 | Humulus lupulus | 2287 | 1 | ATPase of unknown function | Unknown |