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. 2019 Feb 21;20(4):939. doi: 10.3390/ijms20040939

Figure 5.

Figure 5

Local scanning for the start codon selection in archaea. The figure schematizes the different steps of the start codon selection for SD containing archaeal mRNAs. Note that aIF1 facilitates the mRNA binding [72,145]. On the right of the figure, the positions of the TC in PIC0–PREMOTE and PIC1–PIN are compared after superimposition of the 30S bodies. The color code is the same as that in Figure 3 and Figure 4, with light colors for PIC0–PREMOTE and dark colors for PIC1–PIN. For clarity, the mobile wings of aIF2 are omitted. The view shows that aIF2γ does not significantly move in the two conformations, leading to a structural constraint in PIC1-PIN.