Table 4.
Patient-reported outcome measures (pain: VAS and KOOS-pain; function: IKDC, WOMAC, KOOS: symptom, ADL, sport/recreation and QOL).
| Control Group | PRP Group | ||||||
|---|---|---|---|---|---|---|---|
| PROM | MCID | Mean Change | Improved by at Least MCID [%] | Mean Change | Improved by at Least MCID [%] | P a | P b |
| VAS | 2 [12] | 2.36 ± 0.0.09 (3.86–5.20) | 39 | 3.62 ± 0.07 (2.82–4.43) | 65 | 0.027 | 0.046 |
| IKDC | 16.7 [13] | 33.66 ± 0.84 (25.95–41.36) | 83 | 34.74 ± 0.55 (28.17–41.31) | 78 | 0.48 | 0.48 |
| WOMAC | 11.5 [14] | 21.77 ± 0.67 (15.65–27.90) | 65 | 24.77 ± 0.37 (20.40–29.14) | 86 | 0.16 | 0.053 |
| KOOS | |||||||
| Pain | 16.7 [13] | 24.95 ± 0.62 (19.24–30.66) | 65 | 29.50 ± 0.45 (24.18–34.81) | 73 | 0.17 | 0.36 |
| Symptoms | 17.4 [13] | 18.38 ± 0.82 (10.81–25.95) | 48 | 27.93 ± 0.42 (22.89–32.96) | 76 | 0.016 | 0.028 |
| ADL | 18.4 [13] | 24.61 ± 0.74 (17.79–31.43) | 57 | 26.27 ± 0.39 (21.67–30.87) | 76 | 0.18 | 0.1 |
| S/R | 12.5 [13] | 43.75 ± 1.12 (33.43–54.07) | 83 | 34.65 ± 0.76 (25.57–43.74) | 70 | 0.12 | 0.22 |
| QoL | 15.6 [13] | 32.67 ± 1.06 (22.93–42.41) | 70 | 28.43 ± 0.52 (22.23–34.64) | 76 | 0.29 | 0.41 |
a For mean changes; b for % of patients improved by at least MCID. Data are presented as mean ± standard error (CI 95%) unless otherwise indicated. PROM, patient related outcome measures; VAS, visual analogue scale; WOMAC, Western Ontario and McMaster Universities Osteoarthritis Index; IKDC, International Knee Documentation Committee; KOOS, Knee injury and Osteoarthritis Outcome Score; ADL, activities of daily living; S/R, sport/recreation; QOL, quality of life; MCID, Minimal Clinically Important Difference.