ARID1A |
AT-Rich Interaction Domain 1A |
ATM |
ATM Serine/Threonine Kinase |
AKT |
AKT Serine/Threonine Kinase |
ATR |
ATR serine/threonine kinase |
AUC |
Area Under the Curve |
BARD1 |
BRCA1 Associated RING Domain 1 |
BECN1 |
Beclin 1 |
BER |
Base Excision Repair |
BRAF |
B-Raf Proto-Oncogene, Serine/Threonine Kinase |
BRCA |
BRCA, DNA Repair Associated |
BRIP1 |
BRCA1 Interacting Protein C-Terminal Helicase 1 |
CA125 |
Cancer Antigen 125 |
CCNE1 |
Cyclin E1 |
CDKN2A |
Cyclin Dependent Kinase Inhibitor 2A |
CDKN2D |
Cyclin Dependent Kinase Inhibitor 2D |
CDK12 |
Cyclin Dependent Kinase 12 |
CHEK2 |
Checkpoint Kinase 2 |
CICs |
Cortical Inclusion Cysts |
CK7 |
Cytokeratin 7 |
CK20 |
Cytokeratin 20 |
CNAs |
Copy Number Alterations |
CT |
Computer Tomography |
CTNNB1 |
Catenin Beta 1 |
DICER |
Dicer 1, Ribonuclease III |
DNA |
Deoxyribonucleic acid |
EMA |
European Medicines Agency |
EOC |
Epithelial Ovarian Cancer |
ER |
Estrogen Receptor |
FDA |
Food and Drug Administration |
FIGO |
International Federation of Gynecology and Obstetrics |
FOXM1 |
Forkhead Box M1 |
FTSEC |
Secretory Epithelial Cells of the Distal Fallopian Tube |
GAB2 |
GRB2 Associated Binding Protein 2 |
GABRA6 |
Gamma-Aminobutyric Acid Type A Receptor Alpha6 Subunit |
g-H2AX |
Gamma H2A histone family member X |
GEMM |
Genetically Engineered Mouse Models |
GOG |
Gynecologic Oncology Group |
GWAS |
Genome Wide Association Studies |
HDM2 |
HDM2 Proto-Oncogene |
HGSOC |
High Grade Serous Ovarian Cancer |
HIF-1a |
Hypoxia Inducible Factor 1 Subunit Alpha |
HMGA2 |
High Mobility Group AT-Hook 2 |
HNF1b |
HNF1 Homeobox B |
HOXA9 |
Homeobox A9 |
IARC |
International Agency for Research on Cancer |
KRAS |
KRAS Proto-Oncogene, GTPase |
LC3 |
Microtubule Associated Protein 1 Light Chain 3 Alpha |
LOH |
Loss of Heterozygosity |
MAPK |
Mitogen-Activated Protein Kinase 1 |
MECOM |
MDS1 And EVI1 Complex Locus |
MRI |
Magnetic Resonance Imaging |
MRE11A |
MRE11 Homolog, Double Strand Break Repair Nuclease |
MYC |
MYC Proto-Oncogene, BHLH Transcription Factor |
NACT |
Neoadjuvant Chemotherapy |
NCI |
American National Cancer Institute |
NF1 |
Neurofibromin 1 |
NSG |
NOD-SCID IL2R-gammanull
|
OSE |
Ovarian Surface Epithelium |
PALB2 |
Partner and Localizer of BRCA2 |
PARP |
Poly (ADP-Ribose) Polymerase |
PAX8 |
Paired Box 8 |
PDXs |
Patient Derived Xerographs |
PET |
Positron-Emission Tomography |
PI3K |
Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit |
PIK3CB |
Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Beta |
PIK3CA |
Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha |
PR |
Progesterone Receptor |
PTEN |
Phosphatase and Tensin Homolog |
P53 |
Tumor Protein P53 |
RAD50 |
RAD50 Double Strand Break Repair Protein |
RAD51C |
RAD51 Paralog C |
RAS |
KRAS Proto-Oncogene, GTPase |
RB |
RB Transcriptional Corepressor |
ROS |
Radical Oxygen Species |
RTK |
Receptor Tyrosine Kinases |
SCID |
Severe Combined Immunodeficient |
SEER |
Surveillance Epidemiology and End Results |
SET |
Solid pseudo-Endometrioid and/or Transitional Cell Carcinoma-like |
SNPs |
Single Nucleotide Polymorphisms |
STIC |
Serous Tubal Intra Epithelial Carcinoma |
TCGA |
The Tumor Genome Atlas |
UK |
United Kingdom |
VEGF-A |
Vascular Endothelial Growth Factor A |
WDFY2 |
WD Repeat and FYVE Domain Containing 2 |
WHO |
World Health Organization |
WNT |
Wnt Family Member |
WT1 |
Wilms Tumor 1 |